17 Beta-Hydroxysteroid Dehydrogenase Type 7
[Encoded by human HSD17B7 Gene (SDR Family) and expressed in breast, ovaries, pregnant uterus, placenta, testis, thymus, prostate, fetal liver, and some neural tissues, 341-amino acid 38-kD 17-Beta-Hydroxysteroid Dehydrogenase 7 oxidizes or reduces estrogens and androgens. Responsible for biosynthesis of estradiol in the corpus luteum during pregnancy, the membrane-associated phosphorylated enzyme is nearly 75% identical to rodent proteins and contains a short chain dehydrogenase domain. Close to the transmembrane domain, HSD17B7 contains a 28-residue superficial loop: a candidate prolactin receptor (PRLR)-binding domain. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C133406617 Beta-Hydroxysteroid Dehydrogenase Type VII
17-Beta-HSD 7
17-Beta-Hydroxysteroid Dehydrogenase 7
EC 1.1.1.51
Estradiol 17 Beta-Dehydrogenase 7
HSD17B7
Hydroxysteroid (17-Beta) Dehydrogenase 7
17-Beta-HSD 7
17-Beta-Hydroxysteroid Dehydrogenase 7
EC 1.1.1.51
Estradiol 17 Beta-Dehydrogenase 7
HSD17B7
Hydroxysteroid (17-Beta) Dehydrogenase 7
- Amino Acid, Peptide, or Protein
- Enzyme
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