A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
ARHI
[Encoded by human ARHI Gene, the 229-amino acid 26 kD RHO-Related GTP-Binding Protein RHOI (RHO Family) appears to be a tumor suppressor expressed in breast and ovarian epithelial cells, and in heart, liver, pancreas, and brain; expression is absent in breast and ovarian cancer cell lines. Growth factors decrease expression of RHOI Protein, as does WAF1 (CDKN1A). The 229 amino acid protein shares 54% amino acid homology with HRAS and 56-62% homology with RAS-related proteins, and contains a highly conserved GTP-binding domain, a putative effector domain distinct from RAS and RAP proteins, and a C-terminal membrane localization motif. (from SWISS-PROT, OMIM, and NCI) ( NCI )]
UMLS (NCI) C1335619ARHI Protein
RAS Homolog Gene Family, Member I Protein
RAS-Related GTP-Binding Protein Member I Protein
RHO-Related GTP-Binding Protein RHOI
RAS Homolog Gene Family, Member I Protein
RAS-Related GTP-Binding Protein Member I Protein
RHO-Related GTP-Binding Protein RHOI
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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