[A murine monoclonal antibody (MoAb) IgG2a, LL2. MoAb LL2 recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. When labeled with radioisotope, MoAb LL2 targets at tumor cells that express CD22 antigen and deliver cytotoxic radiation that may be used to treat B-cell lineage cancers. ( NCI )]
UMLS (NCI) C0281743 - Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor