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Anti-CD30 Monoclonal Antibody
[A genetically-engineered, chimeric mouse-human, anti-CD30 monoclonal antibody with potential antineoplastic activity. Monoclonal antibody SGN-30 specifically binds to the receptor CD-30, a member of the tumor necrosis factor receptor super-family, which may be overexpressed on the surfaces of Hodgkin's lymphoma cells and anaplastic-large cell lymphoma cells. After binding to CD30, this agent interferes with the G1 phase of the cell cycle, thereby inducing growth arrest and apoptosis in susceptible tumor cell populations. ( NCI )]
UMLS (NCI) C1328236Monoclonal Antibody SGN-30
SGN-30
SGN-30
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor
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