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Anti-CTLA4 Human Monoclonal Antibody CP-675,206
[A monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen-4 (CTLA4), an antigen that is expressed on activated T-cells and exhibits affinity for B7 co-stimulatory molecules. By binding CTLA4, ipilimumab enhances T-cell activation and blocks B7-1 and B7-2 T-cell co-stimulatory pathways. ( NCI )]
UMLS (NCI) C1367202Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody
Ipilimumab
Ticilimumab
Ipilimumab
Ticilimumab
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor
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