Betaglycan
[Encoded by human TGFBR3 Gene, 849-aa 93-kDa (precursor) Transforming Growth Factor Beta Receptor III is a membrane-bound or soluble glycoprotein heavily modified by glycosaminoglycan groups, with regions of similarity to endoglin, and containing a ZP domain. Lacking a recognizable signaling domain, TGFBR3 binds to TGF-Beta and may be a TGFBR and FGFR receptor accessory molecule; it may capture and retain TGF-Beta for presentation to signaling receptors. TGF-beta is a multifunctional cytokine that modulates cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. TGFBR3 can also bind inhibin and function as coreceptor with ActRII; inhibin forms crosslinked complexes with TGFBR3 and ActRII. TGFBR3 also binds beta arrestin 2, which appears to trigger cytoplasmic phosphorylation by TGFBR2. (NCI) ( NCI )]
UMLS (NCI) C0106158- Amino Acid, Peptide, or Protein
- Receptor
Buy website
Medical Clinic. Optician. Pharmacy. Physician. Travel Agency. Hotel reservation. Child Care. Education. Teachers. Lessons. Tests and Exams. Certification. Shopping Center. Store. Real Estate.Affordable prices from $100.
  |
home
