DESERPIDINE
[An ester alkaloid derived from Rauwolfia canescens with antihypertensive activity. Deserpidine is a competitive inhibitor of the angiotensin converting enzyme (ACE). By competing with angiotensin I for ACE, deserpidine blocks the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor. Reduced level of serum angiotensin II causes a decrease in blood pressure. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex. ( NCI )]
UMLS (NCI) C0175158- Organic Chemical
- Pharmacologic Substance
Relation/PAR: (3beta,16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester
[CV490] ANTIHYPERTENSIVES, OTHER
[CV490] ANTIHYPERTENSIVES, OTHER
Relation/CHD: DESERPIDINE 0.5 MG
DESERPIDINE 0.25 MG
DESERPIDINE 0.25 MG
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