GTF2A1

1. [Encoded by human GTF2A1 Gene, TFIIA Alpha p55 is a 55-kDa post-translationally processed precursor of the 35-kD alpha (N-terminal) and 19-kD beta (C-terminal) subunits of general transcription initiation factor TFIIA. These subunits and the 12-kDa gamma subunit (GTF2A2 Gene) form a six strand beta-barrel that interacts with TBP and a separate four-helix bundle positioned just upstream of the TBP-TATA complex. Accurate transcription initiation on class II genes involves ordered assembly of RNA polymerase II and general initiation factors. (NCI) ( NCI )]
   UMLS (NCI) C1336610
   
   TFIIA Alpha p55
   
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance

2. [Encoded by human GTF2A1 Gene, Transcription Initiation Factor IIA Alpha Chain is a 35-kD subunit of general transcription initiation factor TFIIA that is post-translationally processed (N-terminal) with the 19-kD beta subunit (C-terminal) from the 55-kDa TFIIA Alpha p55 precursor. These subunits and the 12-kDa gamma subunit (GTF2A2 Gene) form a six strand beta-barrel that interacts with TBP and a separate four-helix bundle positioned just upstream of the TBP-TATA complex. Accurate transcription initiation on class II genes involves ordered assembly of RNA polymerase II and general initiation factors. (NCI) ( NCI )]
   UMLS (NCI) C1336783
   
   TFIIA p35 Subunit
   Transcription Initiation Factor IIA Alpha Chain
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance

3. [Encoded by human GTF2A1 Gene, Transcription Initiation Factor IIA Beta Chain is a 19-kD subunit of general transcription initiation factor TFIIA that is post-translationally processed (C-terminal) with the 35-kD alpha subunit (N-terminal) from the 55-kDa TFIIA Alpha p55 precursor. These subunits and the 12-kDa gamma subunit (GTF2A2 Gene) form a six strand beta-barrel that interacts with TBP and a separate four-helix bundle positioned just upstream of the TBP-TATA complex. Accurate transcription initiation on class II genes involves ordered assembly of RNA polymerase II and general initiation factors. (NCI) ( NCI )]
   UMLS (NCI) C1336784
   
   TFIIA p19 Subunit
   Transcription Initiation Factor IIA Beta Chain
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance