[Encoded by human GTF3C2 Gene, 110-kD ubiquitous General Transcription Factor IIIC2 Beta Subunit is the beta subunit of general transcription factor GTF3C, a component of RNA polymerase III and essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA. To initiate RNA synthesis, RNA polymerases need GTFs to assemble in a promoter-bound complex and recruit RNA polymerase. GTF3C2 contains stretches of acidic and basic regions, potential acidic and basic helices, and 5 putative WD40 repeats. (NCI) ( NCI )]
UMLS (NCI) C1333806General Transcription Factor IIIC2 Beta Subunit
GTF3C2
TFIIIC110
TFIIIC-Beta
- Amino Acid, Peptide, or Protein
- Biologically Active Substance