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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
N N- N0 N3 NA NB NC ND NE NF NG NH NI NK NL NM NN NO NP NR NS NT NU NV NX NY NZ
NE NE- NEA NEB NEC NED NEE NEF NEG NEI NEL NEM NEN NEO NEP NER NES NET NEU NEV NEW NEX NEZ

Neosporin Ophthalmic

[Any of the sterile, commercial combination preparations, by Pfizer, containing neomycin sulfate and polymyxin B sulfate, as the main active ingredients, for ophthalmic treatments. Polymyxin B sulfate, a polypeptide produced by Bacillus polymyxa, binds to the negatively charged phospholipids in the cell membrane, thereby altering the permeability of the bacterial cytoplasmic membrane. Neomycin sulfate, an aminoglycoside antibiotic, irreversibly binds to the bacterial 30S subunit proteins and 16S rRNA of ribosome, thereby causing misreading and inhibiting protein synthesis which results in bactericidal effect. ( NCI )]
UMLS (NCI) C0722042
 
Organic Chemical
Antibiotic

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