[A vaccine comprised of a recombinant fowlpox virus vector encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM), which may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells. (NCI04) ( NCI )]
UMLS (NCI) C1134570Recombinant Fowlpox-TRICOM Vaccine
rF-TRICOM (B7.1.iCAM1-LFA3-Fowlpox)
- Pharmacologic Substance
- Immunologic Factor