S S S- S0 S1 S2 S3 S4 S5 S6 S7 S8 S9 SA SB SC SD SE SF SG SH SI SJ SK SL SM SN SO SP SQ SR SS ST SU SV SW SY
Signal-Regulatory Protein Beta 1
[Expressed as 2 alternative isoforms in monocytes and dendritic cells by human SIRPB1 Gene (SIRPB Family/Ig Family), N-glycosylated 398-aa 43-kDa (precursor) type I membrane protein Signal-Regulatory Protein Beta 1 is a cell surface Ig-like transmembrane receptor glycoprotein containing an IgV-type domain and 2 IgC1-type domains involved in negative regulation of receptor tyrosine kinase-coupled signaling. Unlike SIRPAs, SIRPB1 lacks a C-terminal cytoplasmic SHP2-binding domain. SIRPB1 interacts with ITAM protein TYROBP/DAP12, resulting in SYK tyrosine kinase recruitment. (NCI) ( NCI )]
UMLS (NCI) C0907306SIRP Beta 1
SIRPB1
SIRPB1
- Amino Acid, Peptide, or Protein
- Receptor
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