T T T, T- T0 T1 T2 T3 T4 T9 TA TB TC TD TE TF TG TH TI TJ TK TL TM TN TO TP TQ TR TS TT TU TV TW TY TZ
Thyroid Stimulating Hormone Receptor
[Encoded by human TSHR Gene (FSH/LSH/TSH GPCR1 Family), alternative long and short isoforms of integral membrane protein Thyroid Stimulating Hormone Receptor act as a Thyrotropin receptor, containing 6 LRR repeats, whose activity is mediated by adenylate cyclase-activating G proteins and controls thyroid cell metabolism. TSHR also acts as a thyrostimulin receptor (GPA2+GPB5). TSHR defects cause hypothyroidism, Graves' disease, euthyroidism or papillary and follicular thyroid neoplasms. (NCI) ( NCI )]
UMLS (NCI) C0034844- Amino Acid, Peptide, or Protein
- Receptor
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