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Tolterodine
[A benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine receptor binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract.. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects. ( NCI )]
UMLS (NCI) C0388753- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Benzhydryl Compounds
Cresols
parasympatholytic agent
Cresols
parasympatholytic agent
Relation/CHD: Tolterodine Tartrate
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