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anti-B7-1
[A humanized IgG1 monoclonal antibody directed against CD80, the natural ligand for the T-cell antigen CD28 which mediates T-cell and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes and is often expressed at low levels on the surfaces of follicular lymphoma cells and other lymphoid malignancies. Galiximab binds to CD80 expressed on the cell surfaces of follicular lymphomas, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). (NCI04) ( NCI )]
UMLS (NCI) C1098262anti-CD80 Antibody
Galiximab
Monoclonal Antibody IDEC-114
Galiximab
Monoclonal Antibody IDEC-114
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor
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