[Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41) ( MSH )]
UMLS (CSP) C0027794 Relation/PAR: congenital nervous system disorder
Relation/CHD: anencephalus
Arnold-Chiari Malformation
ENCEPHALOCELE
meningomyelocele
spina bifida
Meningocele