- 1. AMF
- [Encoded by human GPI Gene (GPI Family), Glucose-6-Phosphate Isomerase, Neuroleukin, and Autocrine Motility Factor function in different capacities. In glycolysis and gluconeogenesis, homodimeric cytoplasmic GPI catalyzes reversible G6P and F6P isomerization. Produced by lectin-stimulated T-cells, secreted non-mitogenic NLK lymphokine acts early in antibody-secreting cell formation to induce Ig secretion. Also a neurotrophic factor for spinal and sensory neurons, NLK exhibits GPI activity. AMF is a 558-amino acid 55-kD autocrine motility polypeptide. The gene product is partly homologous to a conserved region of HTLV-III-LAV external envelope protein. Gene defects cause nonspherocytic hemolytic anemia and hydrops fetalis. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0085144) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 3. Amfetamine
- [powerful central nervous system stimulant and sympathomimetic with multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase; it is also a drug of abuse and a psychotomimetic. ( CSP )] (UMLS (NCI) C0002658) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine
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- 2. AMF Receptor
- [Secreted by tumor cells, autocrine motility factor stimulates tumor motility. Its glycoprotein receptor, Autocrine Mobility Factor Receptor, has some homology to p53. In normal fibroblasts, receptor expression appears to be regulated by cell-cell contact. The level of expression is associated with the pathologic stage and grade of tumor penetration. Positive AMFR expression on tumor cells correlates with poor prognosis in bladder cancer. (from OMIM 603243 and NCI) ( NCI )] (UMLS (NCI) C0147219) =Amino Acid, Peptide, or Protein; Receptor
| - 4. AMFR
- [This gene plays a role in tumor cell motility and is associated with several carcinomas. ( NCI )] (UMLS (NCI) C1332083) AMFR Gene;
Autocrine Motility Factor Receptor Gene; =Gene or Genome |