- 1. 3' 5' exonuclease
- [Three Prime-Five Prime Exonucleases prefer mismatched 3-prime termini, catalyze nucleoside monophosphate excision from 3-prime DNA termini and may be a DNA polymerase III subunit, which does not have intrinsic exonuclease activity. 3-prime terminal nucleotide excision from DNA is required to generate termini for subsequent DNA metabolic pathways. ( NCI )] (UMLS (CSP) C0950448) 3'-5' Exonuclease;
=Amino Acid, Peptide, or Protein; Enzyme | - 21. EXOPHTHALM OPHTHALMOPLEG
- (UMLS (ICD9CM) C0152135) =Disease or Syndrome
|
- 2. 3' exonuclease
- [ ] (UMLS (CSP) C0075028) =Amino Acid, Peptide, or Protein; Enzyme ;
=exonuclease;
| - 22. exophthalmos
- [protrusion of one or both eyeballs; can be congenital and familial, or due to pathology, such as a retroorbital tumor (usually unilateral) or thyroid disease (usually bilateral). ( CSP )] (UMLS (CSP) C0015300) =Disease or Syndrome ;
=autoimmune disease;
Disorder of eye, unspecified;
Disorders of the orbit;
=Basedow's disease |
- 3. 5' 3' exonuclease
- [Five Prime-Three Prime Exonucleases specifically catalyze the hydrolysis of terminal phosphodiester bonds of nucleic acids. Human XRN1 and XRN2 are similar to mouse Dhm1 and yeast dhp1, involved in homologous recombination, meiosis, telomere maintenance, RNA synthesis and RNA trafficking. XRN1 localizes to cytoplasmic complexes of mRNA-degrading enzymes and prefers RNA over DNA substrates. XRN2 promotes transcription termination by 5-prime to 3-prime exonuclease activity and autocatalytic cotranscriptional cleavage that may induce dissociation of RNA polymerase II from the DNA template, but function has not yet been fully determined. ( NCI )] (UMLS (CSP) C0094209) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 23. exoribonuclease
- [A family of enzymes that catalyze the exonucleolytic cleavage of RNA. It includes EC 3.1.13.-, EC 3.1.14.-, EC 3.1.15.-, and EC 3.1.16.-. EC 3.1.- ( MSH )] (UMLS (CSP) C0015301) =Amino Acid, Peptide, or Protein; Enzyme =exonuclease;
|
- 4. 5' exonuclease
- [A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis. ( MSH )] (UMLS (CSP) C0070828) =Amino Acid, Peptide, or Protein; Enzyme =PDE;
| - 24. exoribonuclease H
- [ ] (UMLS (CSP) C0059959) =Amino Acid, Peptide, or Protein; Enzyme
|
- 5. exo alpha sialidase
- [do not confuse with EC 3.2.1.129 or EC 3.2.1.138. ( CSP )] (UMLS (CSP) C0027803) =Amino Acid, Peptide, or Protein; Enzyme =O glycosidase;
| - 25. exoribonuclease II
- [ ] (UMLS (CSP) C0073239) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 6. EXO1
- [Exonuclease 1, encoded by the EXO1 gene, is a 88-kD protein with 5-prime to 3-prime double strand DNA exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different protein isoforms, a and b. (From LocusLink) ( NCI )] (UMLS (NCI) C0059944) =Amino Acid, Peptide, or Protein; Enzyme
| - 26. exoskeleton
- [complex of protein and chitin secreted from epidermis of some invertebrates; it provides an important barrier between animals and the external environment. ( CSP )] (UMLS (CSP) C0596796) =Organism Attribute =morphology;
|
- 7. EXO1
- [This gene plays a role in DNA metabolic processes during stromal differentiation. ( NCI )] (UMLS (NCI) C1333365) EXO1 Gene;
Exonuclease 1 Gene;
=Gene or Genome | - 27. Exostoses (multiple) 1
- [Multiple exostoses type 1 gene product, one of three EXT genetic loci involved in hereditary multiple exostoses. EXT1 protein is a transmembrane glycoprotein glycosyltransferase involved in the biosynthesis of heparan sulfate, and a putative tumor suppressor. ( NCI )] (UMLS (NCI) C0537447) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 8. exocrine gland
- [gland that secretes its products through ducts or canals, such as sweat glands or mammary glands. ( CSP )] (UMLS (CSP) C0015282) =Body Part, Organ, or Organ Component ;
=Normal Tissue;
=Gastrointestinal Tract, Pancreas;
Genital System, Male, Prostate;
Head and Neck, Salivary Glands;
salt gland;
sebaceous gland;
sudiferous gland;
mammary | - 28. Exostoses (Multiple) 1 Gene
- [This gene plays a role in heparin/heparin sulfate biosynthesis, axon guidance and biogenesis/cell organization. ( NCI )] (UMLS (NCI) C0694878) =Gene or Genome
|
- 9. exocrine pancreas
- [The major component (about 80%) of the PANCREAS composed of acinar functional units of tubular and spherical cells. The acinar cells synthesize and secrete several digestive enzymes such as TRYPSINOGEN; LIPASE; AMYLASE; and RIBONUCLEASE. Secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the DUODENUM. ( MSH )] (UMLS (CSP) C0553695) =Body Part, Organ, or Organ Component
| - 29. Exostoses (multiple) 2
- [Multiple exostoses type 2 gene product, one of three EXT genetic loci involved in hereditary multiple exostoses. EXT2 protein is a glycosyltransferase involved in the biosynthesis of heparan sulfate, and a putative tumor suppressor. ( NCI )] (UMLS (NCI) C0529768) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 10. Exocrine Pancreas Neoplasm
- (UMLS (NCI) C0345920) =Neoplastic Process
| - 30. Exostoses (Multiple) 2 Gene
- [This gene is involved in the heparin/heparin sulfate biosynthesis, cell organization/biogenesis and development of the cytoskeleton in chondrocytes. ( NCI )] (UMLS (NCI) C0694879) =Gene or Genome ;
|
- 11. exocytosis
- [cellular release of material within membrane-limited vesicles by fusion of the vesicles with the cell membrane. ( CSP )] (UMLS (CSP) C0015283) =Cell Function ;
=membrane activity;
| - 31. Exostoses (Multiple)-Like 1 Gene
- [This gene plays a role in carbohydrate metabolism and the biosynthesis of heparin/heparin sulfate. ( NCI )] (UMLS (NCI) C1333366) EXTL1;
EXTL1 Gene;
=Gene or Genome |
- 12. exoenzyme
- [enzyme that acts outside the cells in which it originates. ( CSP )] (UMLS (CSP) C0596543) =Amino Acid, Peptide, or Protein; Enzyme =enzyme;
| - 32. Exostoses (Multiple)-Like 2 Gene
- [This gene is involved in the biosynthesis of heparin/heparin sulfate and carbohydrate metabolism. ( NCI )] (UMLS (NCI) C1333367) EXTL2;
EXTL2 Gene;
=Gene or Genome |
- 13. Exogenous
- [Happening or arising or located outside or beyond some limits, or especially, some surface. ( NCI )] (UMLS (NCI) C0205101) =Spatial Concept
| - 33. Exostoses (Multiple)-Like 3 Gene
- [This gene plays a role in signal transduction, carbohydrate metabolism and the biosynthesis of heparin/heparin sulfate. ( NCI )] (UMLS (NCI) C1367595) EXTL3;
EXTL3 Gene =Gene or Genome |
- 14. exon
- [The sequences of a gene that are present in the final, mature, spliced messenger RNA molecule from that gene. ( NCI )] (UMLS (CSP) C0015295) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
| - 34. Exostosin-L
- [Encoded by human EXTL1 Gene (EXT Family), 676-aa 75-kDa Exostosin-Like 1 is a type II membrane protein glycosyltransferase of the endoplasmic reticulum with strong sequence similarity to EXT1 and EXT2 and likely involved in chain elongation during heparan sulfate and heparin biosynthesis. (NCI) ( NCI )] (UMLS (NCI) C1333484) Exostosin-Like 1 Protein;
EXTL1;
Multiple Exostosis-Like Protein =Amino Acid, Peptide, or Protein; Enzyme |
- 15. Exon Non-Synonymous Mutation
- [A mutation in which a base change results in substitution of one amino acid for another. This change may result in alteration of the protein's activity or stability. ( NCI )] (UMLS (NCI) C0599155) =Genetic Function ;
| - 35. Exostosin-Like 3 Protein
- [Ubiquitously expressed by human EXTL3 Gene (EXT Family), 919-aa 105-kDa Exostosin-Like 3 is a type II membrane protein glycosyltransferase of the endoplasmic reticulum likely involved in chain initiation and elongation during heparan sulfate/heparin biosynthesis. EXTL3 contains a highly conserved C-terminal region, common to other EXT proteins. (NCI) ( NCI )] (UMLS (NCI) C1308412) EXTL3;
EXT-Related Protein 1;
Hereditary Multiple Exostoses Gene Isolog;
Multiple Exostosis-Like Protein 3;
Putative Tumor Suppressor Protein EXTL3 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 16. exonuclease
- [enzymes that catalyze the release of mononucleotides by the hydrolysis of the terminal bond of deoxyribonucleotide or ribonucleotide chains, EC 3.1.-, including EC 3.1.11, 3.1.15 and EC 3.1.16. ( CSP )] (UMLS (CSP) C0015296) =Amino Acid, Peptide, or Protein; Enzyme =Ester Hydrolase;
=DNA Exonuclease;
exoribonuclease;
3' exonuclease | - 36. EXOSTOSIS EXT EAR CANAL
- [ ] (UMLS (ICD9CM) C0155411) =Disease or Syndrome ;
|
- 17. exopeptidase
- [nonEC category which corresponds to EC 3.4.11, EC 3.4.13, EC 3.4.14, EC 3.4.15, EC 3.4.16, EC 3.4.17, EC 3.4.18, and EC 3.4.19. ( CSP )] (UMLS (CSP) C0117059) =Amino Acid, Peptide, or Protein; Enzyme ;
=Enzymes, Proteolytic;
=aminopeptidase;
carboxypeptidase;
peptidyl dipeptidase | - 37. EXOSTOSIS OF JAW
- [ ] (UMLS (ICD9CM) C0155955) =Disease or Syndrome ;
|
- 18. Exophiala
- [A normally saprophytic mitosporic Chaetothyriales fungal genus. Infections in humans include phaeohyphomycosis, peritonitis, and chromoblastomycosis. Exophiala jeanselmei (previously Phialophora jeanselmei) is an etiological agent of maduromycosis. ( MSH )] (UMLS (CSP) C0015298) =Fungus ;
| - 38. EXOSTOSIS OF ORBIT
- [ ] (UMLS (ICD9CM) C0155275) =Disease or Syndrome ;
|
- 19. Exophiala dermatitidis
- [ ] (UMLS (CSP) C0031521) =Fungus ;
| - 39. Exosurf Neonatal
- (UMLS (NCI) C0247189) =Lipid; Pharmacologic Substance ;
|
- 20. EXOPHORIA
- [ ] (UMLS (ICD9CM) C0152217) =Disease or Syndrome ;
| - 40. exotoxin
- [toxic substances produced by certain bacteria, that are found outside the bacterial cell or free in the culture medium; they are heat labile proteins and are among the most poisonous substances known; some fungi also produce exotoxins. ( CSP )] (UMLS (CSP) C0314768) =Biologically Active Substance; Hazardous or Poisonous Substance =bacterial toxin;
=botulin;
diphtheria toxin;
streptokinase;
tetanus toxin;
staphylococcal exotoxin |
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