10-chloro-4-hydroxy-6-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-2,8,10,12-tetraen-5-one
[A benzodiazepine derivative with antidepressant, sedative, hypnotic and anticonvulsant properties. Temazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreases neuronal excitability. ( NCI )]
UMLS (NCI) C0039468- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Benzodiazepinones
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS
Relation/CHD: TEMAZEPAM 15 MG
TEMAZEPAM 30 MG
TEMAZEPAM 7.5 MG
TEMAZEPAM 30 MG
TEMAZEPAM 7.5 MG
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