[Encoded by human AMHR2 Gene, the 573-amino acid 62.7 kD Anti-Mullerian Hormone Receptor Type II Ser/Thr protein kinase (TGFB Receptor Family) is a type I membrane protein. Type II receptors bind ligand but require a type I receptor for signal transduction. Anti-Mullerian Hormone (AMH/MIS/MIF), produced by Sertoli cells, induces regression of Mullerian ducts, which differentiate into the uterus and fallopian tubes. Type I persistent Mullerian duct syndrome is caused by AMH gene mutation; type II syndrome is due to AMHR mutation. (OMIM, Swiss-Prot, and NCI) ( NCI )]
UMLS (NCI) C0380056 - Amino Acid, Peptide, or Protein
- Receptor