[A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. (NCI04) ( NCI )]
UMLS (NCI) C0054836 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: Carbazoles
Propanolamines
[CV100] BETA-BLOCKERS/RELATED
Relation/CHD: CARVEDILOL 12.5 MG
CARVEDILOL 25 MG
CARVEDILOL 6.25 MG
CARVEDILOL 3.125 MG