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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
C C- C1 C3 C5 C6 C7 CA CB CC CD CE CF CG CH CI CJ CK CL CM CN CO CP CQ CR CS CT CU CV CW CX CY CZ
CC CC- CC4 CC5 CCA CCB CCC CCD CCE CCF CCG CCH CCI CCK CCL CCM CCN CCQ CCR CCS

CCNB

[Cyclin B1 is essential for control of the G2/M transition and the gene is expressed predominantly in the G2/M phase of cell division. Complexed with p34(cdc2), cyclin B1 forms mitosis-promoting factor (MPF), a serine/threonine kinase holoenzyme complex. Cyclin B1 imparts substrate specificity to MPF. Phosphorylation of cyclin B1 regulates nuclear translocation of MPF during prophase, essential for the induction and coordination of M-phase events. During cell cycle progression, a change in PLK1 kinase activity appears to phosphorylate cyclin B1 and stimulate nuclear entry of cyclin B1. (from SWISS-PROT P14635, OMIM 123836, and NCI) ( NCI )]
UMLS (NCI) C0385333
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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