CEFOTETAN
[A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic derived from cephalosporium. The bactericidal activity of cefotetan disodium is caused by an inhibition of bacterial cell wall synthesis via inhibition of cross-linking of peptidoglycans. This results in a reduction of cell wall stability and causes cell lysis. Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to first-generation cephalosporins. ( NCI )]
UMLS (NCI) C0007555- Organic Chemical
- Antibiotic
Relation/PAR: Tetrazoles
Cephalosporanic Acids
[AM102] CEPHALOSPORINS, 2ND GENERATION
Cephalosporanic Acids
[AM102] CEPHALOSPORINS, 2ND GENERATION
Relation/CHD: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl)carbonyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, Disodium Salt,(6R-(6alpha,7alpha))-
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