Calcipotriene
[A synthetic vitamin D derivative usually formulated for topical dermatological use, antipsoriatic Calcipotriene (calcipotriol) competes equally with active 1,25-hydroxy-2D3 (the natural form of vitamin D) for 1,25-hydroxy-2D3 receptors in regulating cell proliferation and differentiation. It induces differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and leads to normalization of epidermal growth. (NCI04) ( NCI )]
UMLS (NCI) C0065767- Organic Chemical
- Pharmacologic Substance
Relation/PAR: (1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
[DE802] ANTIPSORIATICS, TOPICAL
[DE802] ANTIPSORIATICS, TOPICAL
Relation/CHD: CALCIPOTRIENE 0.005 %
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