TAF11

1. [This gene plays a role in transcriptional initiation and signal transduction modulation. ( NCI )]
   UMLS (NCI) C1336561
   
   TAF11 Gene
   TAF11 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 28kDa Gene
   
    

   Gene or Genome
   

2. [Encoded by human TAF11 Gene (TAF2I Family), 211-aa 23-kDa nuclear TBP-Associated Factor 11 is a small subunit of all TFIID complexes that interacts directly with TBP, interacts with TAFII18, and interacts with TAF13 to form a heterodimer with a structure similar to the histone core structure. TBP and TAFII18 bind to distinct domains of TAF11. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )]
   UMLS (NCI) C1336580
   
   TAF11 RNA Polymerase II
   TAFII28
   TATA Box Binding Protein-Associated Factor RNA Polymerase II I 28kD
   TBP-Associated Factor 11
   TBP-Associated Factor 28kDa
   TBP-Associated Factor RNA Polymerase II I 28kD
   TFIID Subunit p30-Beta
   Transcription Initiation Factor TFIID 28 kD Subunit
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance