UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
T T T, T- T0 T1 T2 T3 T4 T9 TA TB TC TD TE TF TG TH TI TJ TK TL TM TN TO TP TQ TR TS TT TU TV TW TY TZ
TFA TFC TFD TFE TFF TFI TFP TFR

TFIIE Subunit Gene

[TFIIE Subunit Genes encode 2 subunit proteins of 56 kD and 34 kD. TFIIE is a heterotetramer of 2 alpha and 2 beta subunits, both subunits being required for optimal basal-level transcription. Both subunits are essential to form a stable preinitiation complex. High levels of gene transcription by RNA polymerase II depend on high rates of transcription initiation and reinitiation. Initiation requires recruitment of the complete transcription machinery to a promoter, a process facilitated by activators and chromatin remodeling factors. Reinitiation occurs through a different pathway. After initiation, a subset of the transcription machinery remains at the promoter, forming a platform for assembly of a second transcription complex as a scaffold for formation of a functional reinitiation complex. Formation of this scaffold depends on ATP and TFIIH. Some activators and Mediator may promote high levels of transcription. (from OMIM 189962). ( NCI )]
UMLS (NCI) C1336613
 
Gene or Genome


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