T T T, T- T0 T1 T2 T3 T4 T9 TA TB TC TD TE TF TG TH TI TJ TK TL TM TN TO TP TQ TR TS TT TU TV TW TY TZ
TNF Receptor-Associated Factor 2
[TRAF2 is a homo- or (with TRAF1) heterodimer adaptor protein for TNFR1, TNFR2, and CD40 that mediates activation of NFKB. TRAF2 contains a TRAF motif known to bind kinases involved in TRAF-mediated signaling, a Zn RING finger, and cysteine/histidine-rich motifs. E2F1 can down regulate TRAF2 and inhibit anti-apoptotic NFKB signals. (from OMIM 601895 and NCI) ( NCI )]
UMLS (NCI) C0258441- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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