- 1. FYN
- [This gene plays a role in the regulation of cell growth and proliferation. ( NCI )] (UMLS (NCI) C0812303) FYN Gene;
FYN Oncogene Related to SRC, FGR, YES Gene =Gene or Genome | - 3. FYN-Related Kinase
- [Encoded by human FRK Gene (SRC Family), 505-aa 58-kDa FYN-Related Kinase (tyrosine kinase) contains a putative ATP-binding motif, tyrosine kinase motifs, and SH2 and SH3 domains. FRK lacks a myristylation signal, has autophosphorylation activity, is C-terminal tyrosine phosphorylated by CSK, and may function during G1/S and suppress growth. (NCI) ( NCI )] (UMLS (NCI) C1384553) GTK;
GTK Homolog;
Nuclear Tyrosine Protein Kinase RAK;
RAK;
Tyrosine-Protein Kinase FRK =Amino Acid, Peptide, or Protein; Enzyme |
- 2. FYN-Associated Phosphoprotein SKAP55 Homologue
- [Expressed in lung, skeletal muscle, kidney, peripheral leukocytes, spleen, brain, placenta, heart, prostate, testis, ovary, and colon by human SCAP2 Gene (SRC Kinase Family), 359-aa SRC Family Associated Phosphoprotein 2, an adaptor protein implicated in myeloid differentiation and growth arrest, is thought to play a role in SRC signal transduction pathways of tyrosine and nontyrosine kinase receptors. Like SKAP55, SKAP55R contains a PH domain, multiple tyrosine phosphorylation sites, and an SH3 domain. Unlike SKAP55, SKAP55R has an N-terminal coiled-coil domain. SKAP55R and SKAP55 are phosphorylated by FYN, but not LCK or ZAP70. Unlike SKAP55, SKAP55R is not constitutively phosphorylated in T cells. FYB in T cells binds SKAP55 and SKAP55R through their SH3 domains. (NCI) ( NCI )] (UMLS (NCI) C0755813) SAPS;
SCAP2;
SKAP55R;
SKAP55-Related Protein;
SRC Family Associated Phosphoprotein 2;
SRC Kinase-Associated Phosphoprotein of 55-Related Protein;
SRC-Associated Adaptor Protein;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | |
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