UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
H H+ H1 HA HB HC HD HE HF HG HH HI HK HL HM HN HO HP HQ HR HS HT HU HV HX HY HZ
HK HK HKI HKK
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1. H1 kinase
[ ] (UMLS (CSP) C0599716) =Amino Acid, Peptide, or Protein; Enzyme
3. HK
[A special administrative region of China, bordering the South China Sea and China. (NCI) ( NCI )] (UMLS (NCI) C0019907) =Geographic Area ;
2. H2K antigen
[ ] (UMLS (CSP) C0599838) =Amino Acid, Peptide, or Protein; Immunologic Factor
4. HKI-272
[An orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile, irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. HKI-272 binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. HKI-272 also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. ( NCI )] (UMLS (NCI) C1454298) =Organic Chemical; Pharmacologic Substance ;

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