UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM - Terms starting with ‘I’

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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM

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1. N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide: [A nonsteroidal arylsulfonamide with anti-inflammatory properties. Nimesulide inhibits the cyclooxygenase-mediated conversion of arachidonic acid to pro-inflammatory prostaglandins. Modestly selective for COX-2, this agent binds to the enzyme, thereby inactivating it. Nimesulide may inhibit some carcinogenic COX-2-related carcinogenic effects on xenobiotic metabolism, apoptosis, immune surveillance and angiogenesis (overexpressed COX-2 in tumor epithelial cells enhances production of vascular growth factors and the formation of capillary-like networks). (NCI04) ( NCI )] (UMLS (NCI) C0132515) =Organic Chemical; Pharmacologic Substance ;

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