- 1. O glycosidase
- [ ] (UMLS (CSP) C0597123) =Amino Acid, Peptide, or Protein; Enzyme =glycosidase;
=alpha galactosidase; alpha glucosidase; amylase; beta galactosidase; beta glucosidase; beta N acetylhexosaminidase; acid maltase; glucocerebrosidase; beta glucuronidase; chondroitinase; mannosidase; lysozyme; exo alpha sialidase; beta fructofuranosidase; LACTASE; N acetylglucosaminidase | - 3. OGX-011
- [A mixed-backbone antisense oligodeoxynucleotide with chemosensitizing properties. OGX-011 inhibits testosterone-repressed prostate message-2 (TRPM-2). Administration of OGX-011 abrogates the anti-apoptotic effect of TRPM-2, thereby sensitizing cells to chemotherapy and resulting in tumor cell death. TRPM-2 is an anti-apoptotic clusterin that is overexpressed by prostate cancer cells and is associated with chemoresistance. (NCI04) ( NCI )] (UMLS (NCI) C1328699) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
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