UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM - Terms starting with ‘C’

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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

T T T, T- T0 T1 T2 T3 T4 T9 TA TB TC TD TE TF TG TH TI TJ TK TL TM TN TO TP TQ TR TS TT TU TV TW TY TZ

TFA TFC TFD TFE TFF TFI TFP TFR

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1. TF (c)-KLH conjugate vaccine: [A vaccine containing a clustered pancarcinoma carbohydrate antigen, Thomsen-Friedenreich (TF) antigen, conjugated with keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. TF antigen is a disaccharide epitope (galactose-beta1-3-N-acetylgalactose), normally O-linked to serine or threonine of tumor associated epithelial mucins. This vaccine contains the TF epitope cluster (c) that is synthesized by linking 3 copies of the TF epitope on a threonine backbone to achieve the essential immunogenic structure. KLH is a hapten carrier and serves as an immunostimulant to improve immune recognition. Vaccination with TF(c)-KLH peptide vaccine may produce antibodies and elicit a cytotoxic T lymphocyte (CTL) response against those tumor cells expressing TF antigen, resulting in decreased tumor growth. ( NCI )] (UMLS (NCI) C0796636) TF(c)-KLH;
TF(c)-KLH Conjugate Vaccine;
vaccine, TF (c)-KLH conjugate;
vaccine, TF(c)-KLH conjugate;
=Pharmacologic Substance; Immunologic Factor ;

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