- 101. Dolastatin 15
- [A depsipeptide originally isolated from the marine mollusk Dolabella auricularia with potential antineoplastic activity. Less potent than the structurally-related compound dolastatin 10, dolastatin 15 binds weakly to tubulin and blocks microtubule assembly, thereby inhibiting mitosis. Dolastatin 15 also induces tumor cell apoptosis through a mechanism involving bcl-2, an oncoprotein that is overexpressed in some cancers. (NCI04) ( NCI )] (UMLS (NCI) C0170214) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 151. Dopamine Receptor D2 A2 Allele
- [Human DRD2 Gene at 11q23 encodes Dopamine Receptor D2, a G-protein coupled receptor that inhibits adenylyl cyclase activity. Missense mutation in DRD2 causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing results in two different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. Different alleles are associated with increased incidence of substance abuse. (NCI) ( NCI )] (UMLS (NCI) C1333252) DRD2 2 Allele;
DRD2 A2 Allele;
=Gene or Genome ;
|
- 102. dolichol
- [20-unit isoprenoid found in eukaryotes; serves as membrane anchor for oligosaccharide assembly in rough endoplasmic reticulum during protein glycosylation. ( CSP )] (UMLS (CSP) C0012990) =Lipid; Biologically Active Substance ;
=terpene;
| - 152. Dopamine Receptor D2 Gene
- [This gene plays an inhibitory role in the regulation of adenylyl cyclase activity. ( NCI )] (UMLS (NCI) C1333253) DRD2;
DRD2 Gene;
=Gene or Genome ;
|
- 103. Dolobid
- (UMLS (NCI) C0699201) =Organic Chemical; Pharmacologic Substance ;
| - 153. Dopamine Receptor D4 Gene
- [This gene plays a role in G protein-coupled receptor signal transduction and inhibits adenylyl cyclase activity. ( NCI )] (UMLS (NCI) C1333254) DRD4;
DRD4 Gene;
=Gene or Genome ;
|
- 104. Dolophine
- (UMLS (NCI) C0699057) =Organic Chemical; Pharmacologic Substance
| - 154. Dopamine Receptor D5 Gene
- [This gene plays a regulatory role in adenylate cyclase activity and intracellular cAMP store accumulation. The gene is thought to act as a stimulus in both activities. ( NCI )] (UMLS (NCI) C1333255) DRD5;
DRD5 Gene;
=Gene or Genome ;
|
- 105. dolphin (fish)
- [ ] (UMLS (CSP) C1101834) =Fish
| - 155. dopamine uptake complex
- [A dopamine plasma membrane transporter protein complex located on the membrane of dopaminergic neurons. The complex includes homo-oligomers of the DAT Dopamine Transporter. ( MSH )] (UMLS (CSP) C0114839) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 106. dolphin (mammal)
- [Mammals of the families Delphinidae (ocean dolphins), Iniidae, Lipotidae, Pontoporiidae, and Platanistidae (all river dolphins). Among the most well-known species are the BOTTLE-NOSED DOLPHIN and the KILLER WHALE (a dolphin). The common name dolphin is applied to small cetaceans having a beaklike snout and a slender, streamlined body, whereas PORPOISES are small cetaceans with a blunt snout and rather stocky body. (From Walker's Mammals of the World, 5th ed, pp978-9) ( MSH )] (UMLS (CSP) C0013005) =Mammal
| - 156. Doppler blood flow measurement
- [ ] (UMLS (CSP) C0599582) =Diagnostic Procedure ;
|
- 107. Domain model
- [Holds a sub-set of the RIM that is the domain information model for the committee identified by the rest of the Subject Area name. ( HL7V3.0 )] (UMLS (HL7) C1554088) =Idea or Concept =MDFSubjectAreaPrefix;
| - 157. Doppler blood flowmeter
- [ ] (UMLS (CSP) C0599583) =Manufactured Object ;
|
- 108. Dome of Bladder
- (UMLS (NCI) C0496827) =Neoplastic Process
| - 158. Doppler Echocardiography
- [A procedure that uses sound waves to measure characteristics of disturbed bood flow, such as direction, velocity and turbulence. This enables the examiner to differentiate between normal and abnormal flow patterns and, in some cases, to quantitate those characteristics that are helpful in determining the severity of abnormal flow states. ( NCI )] (UMLS (NCI) C0013520) =Diagnostic Procedure ;
|
- 109. Domeboro
- (UMLS (NCI) C0699643) =Organic Chemical; Pharmacologic Substance ;
| - 159. Doppler OCT
- [Optical Coherence Tomography (OCT) combines the principles of ultrasound with the imaging performance of a microscope. OCT uses infrared light waves that reflect off the internal microstructure within the biological tissues. The frequencies and bandwidths of infrared light are orders of magnitude higher than medical ultrasound signals, resulting in greatly increased image resolution, 8-25 times greater than any existing modality. In addition to providing high-level resolutions for the evaluation of microanatomic structures OCT is also able to provide information regarding tissue composition. ( NCI )] (UMLS (CSP) C0920367) Optical Coherence Tomography =Diagnostic Procedure ;
|
- 110. domestic animal
- [animals which have become adapted through breeding in captivity to a life intimately associated with man; prefer indexing specific animal, treed elsewhere, when possible. ( CSP )] (UMLS (CSP) C0003063) =Animal ;
| - 160. Doppler Ultrasound
- [Diagnostic imaging that uses sound waves (ultrasound) applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. ( NCI )] (UMLS (NCI) C0162481) =Diagnostic Procedure
|
- 111. domestic bird
- [ ] (UMLS (CSP) C0324556) =Bird
| - 161. Doppler velocimetry
- [ ] (UMLS (CSP) C0598596) =Natural Phenomenon or Process
|
- 112. Domestic Injury
- (UMLS (NCI) C0856240) =Injury or Poisoning
| - 162. Dopram
- (UMLS (NCI) C0699979) =Organic Chemical; Pharmacologic Substance ;
|
- 113. Domestic partner
- [Person declares that a domestic partner relationship exists. ( HL7V3.0 )] (UMLS (HL7) C1549111) =Finding =marital status;
MaritalStatus | - 163. Doqualast
- (UMLS (NCI) C0058704) =Organic Chemical; Pharmacologic Substance
|
- 114. domestic partner
- [The player of the role cohabits with the scoping person but is not the scoping person's spouse. ( HL7V3.0 )] (UMLS (HL7) C1609628) =Intellectual Product =Family Member;
| - 164. Doranidazole
- (UMLS (NCI) C0966231) =Organic Chemical; Pharmacologic Substance ;
|
- 115. Domestic Partnership
- [A person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered. ( NCI )] (UMLS (NCI) C0683559) =Social Behavior ;
| - 165. Doripenem
- (UMLS (NCI) C0389169) =Organic Chemical; Pharmacologic Substance
|
- 116. domestic violence
- [deliberate, often repetitive, physical abuse by one family member against another: marital partners, parents, children, siblings, or any other member of a household; covers abuse of cohabiting partners (homo and heterosexual). ( CSP )] (UMLS (CSP) C0206073) =Mental or Behavioral Dysfunction =violence;
=child abuse;
spouse abuse | - 166. dorsal acoustic stria
- [ ] (UMLS (CSP) C0175454) =Body Part, Organ, or Organ Component
|
- 117. Dominant Negative Receptor
- [A Dominant Negative Receptor inhibits the function of an associated protein, typically an alternate form of the same type receptor. ( NCI )] (UMLS (NCI) C1333312) =Amino Acid, Peptide, or Protein; Receptor
| - 167. Dorsal and dorsolumbar fusion, anterior technique
- [ ] (UMLS (ICD9CM) C0186042) =Therapeutic or Preventive Procedure
|
- 118. Dominican
- [Denotes the inhabitants of the Dominican Republic, a person from there, or their descendants elsewhere. ( NCI )] (UMLS (NCI) C1328872) =Population Group; ;
=Hispanic;
| - 168. Dorsal and dorsolumbar fusion, posterior technique
- [ ] (UMLS (ICD9CM) C0186044) =Therapeutic or Preventive Procedure
|
- 119. Domiodol
- (UMLS (NCI) C0048365) =Organic Chemical; Pharmacologic Substance
| - 169. Dorsal Cochlear Nucleus
- (UMLS (NCI) C0175499) =Body Part, Organ, or Organ Component
|
- 120. domoic acid
- [ ] (UMLS (CSP) C0058678) =Organic Chemical; Pharmacologic Substance
| - 170. dorsal column
- [dorsal portion of the white matter of the spinal cord; consists primarily of axons that relay somatic sensory information to the medulla. ( CSP )] (UMLS (CSP) C0458459) =Body Part, Organ, or Organ Component =Medulla Spinalis;
|
- 121. Domoprednate
- (UMLS (NCI) C0058679) =Steroid; Pharmacologic Substance
| - 171. dorsal efferent motor nucleus
- [ ] (UMLS (CSP) C1537008) =Body Part, Organ, or Organ Component
|
- 122. Domoso
- (UMLS (NCI) C0729121) =Organic Chemical; Pharmacologic Substance
| - 172. dorsal horn
- [the dorsal section of the gray matter of the spinal cord; contains sensory nuclei that are relay sites for somatosensory information entering the spinal cord. ( CSP )] (UMLS (CSP) C0228575) =Body Part, Organ, or Organ Component =Medulla Spinalis;
|
- 123. Domperidone
- [A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms. ( MSH )] (UMLS (NCI) C0013015) =Organic Chemical; Pharmacologic Substance ;
| - 173. Dorsal Horn of the Spinal Cord
- (UMLS (NCI) C0228564) =Body Part, Organ, or Organ Component
|
- 124. Donaxin
- (UMLS (NCI) C0061860) =Organic Chemical
| - 174. Dorsal Metacarpal Artery
- (UMLS (NCI) C0447094) =Body Part, Organ, or Organ Component
|
- 125. Donepezil
- [The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby blocking the hydrolysis of the neurotransmitter acetylcholine and, consequently, increasing its activity. This agent may improve neurocognitive function in Alzheimer's disease, reduce sedation associated with opioid treatment of cancer pain, and improve neurocognitive function in patients who have received radiation therapy for primary brain tumors or brain metastases. ( NCI )] (UMLS (NCI) C0527316) =Organic Chemical; Pharmacologic Substance ;
=E 2020;
[CN900] CNS MEDICATIONS, OTHER =Donepezil Hydrochloride | - 175. Dorsal Metatarsal Vein
- (UMLS (NCI) C0835053) =Body Part, Organ, or Organ Component
|
- 126. Donepezil Hydrochloride
- [The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby blocking the hydrolysis of the neurotransmitter acetylcholine and, consequently, increasing its activity. This agent may improve neurocognitive function in Alzheimer's disease, reduce sedation associated with opioid treatment of cancer pain, and improve neurocognitive function in patients who have received radiation therapy for primary brain tumors or brain metastases. ( NCI )] (UMLS (NCI) C0771848) DONEPEZIL HYDROCHLORIDE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=Donepezil;
=DONEPEZIL HYDROCHLORIDE 5 MG;
DONEPEZIL HYDROCHLORIDE 10 MG;
| - 176. dorsal motor nucleus
- [parasympathetic nucleus of the medulla; lateral or dorsolateral to the hypoglossal nucleus in the open medulla and dorsal to the hypoglossal nucleus in the closed medulla; composed of small cells supplying preganglionic fibers by way of the vagus (and bulbar accessory) nerves to terminal ganglia for relay to viscera of the thorax and abdomen. ( CSP )] (UMLS (CSP) C0596458) =Body Part, Organ, or Organ Component =medulla oblongata;
|
- 127. Donepezil/Vitamin E
- (UMLS (NCI) C0935698) =Therapeutic or Preventive Procedure
| - 177. Dorsal Nasal Artery
- (UMLS (NCI) C0226194) =Body Part, Organ, or Organ Component
|
- 128. Donitriptan
- (UMLS (NCI) C0769585) =Organic Chemical; Pharmacologic Substance ;
| - 178. Dorsal Nucleus of the Vagus Nerve
- (UMLS (NCI) C0926535) nucleus alaris;
nucleus dorsalis nervi vagi;
nucleus vagalis dorsalis =Body Part, Organ, or Organ Component |
- 129. Donnan effect on cell
- [ ] (UMLS (CSP) C0684211) =Organ or Tissue Function ;
| - 179. Dorsal or lateral slit of prepuce
- [ ] (UMLS (ICD9CM) C0177145) =Therapeutic or Preventive Procedure
|
- 130. Donnatal
- [A combination agent, comprised of belladonna alkaloids and Phenobarbital, with gastrointestinal anticholinergic activity. The belladonna alkaloids produce an anticholinergic effect by the competitive inhibition of acetylcholine at the parasympathetic neuro-effector junction, and the barbiturates produce a sedative effect probably as a result of their inhibition of synaptic neurotransmitters in the central nervous system (CNS). ( NCI )] (UMLS (NCI) C0378883) =Organic Chemical; Pharmacologic Substance
| - 180. dorsal raphe nucleus
- [nucleus of closely packed, deeply staining cells in the ventral part of the periaqueductal gray; a major source of ascending, serotonergic fibers; appear to be important in regulation of sleep. ( CSP )] (UMLS (CSP) C0175392) =Body Part, Organ, or Organ Component =mesencephalon;
|
- 131. Donor
- [In some organ transplantation services and rarely in transfusion services a donor will be a target participant in the service. However, in most cases transplantation is decomposed in three services: explantation, transport, and implantation. The identity of the donor (recipient) is often irrelevant for the explantation (implantation) service. ( HL7V3.0 )] (UMLS (HL7) C1547101) =Idea or Concept =Relationship modifier;
direct target | - 181. Dorsal Region of Foot
- (UMLS (NCI) C0230462) =Body Part, Organ, or Organ Component
|
- 132. Donor
- [One that contributes something. ( NCI )] (UMLS (NCI) C0013018) =Human
| - 182. dorsal respiratory center
- [ ] (UMLS (CSP) C1537009) =Body Location or Region
|
- 133. Donor
- [individual organism that supplies tissue to be used in another body, as a person who furnishes an organ for transplantation in a histocompatible recipient. ( CSP )] (UMLS (NCI) C0040288) =Population Group =tissue resource/registry;
=blood donor;
| - 183. dorsal root
- [comprises the central branches of the dorsal root ganglion cells and connects to the gray matter of the spinal cord; each spinal nerve has one. ( CSP )] (UMLS (CSP) C0205955) =Body Part, Organ, or Organ Component ;
=Medulla Spinalis;
|
- 134. Donor Registration Number
- (UMLS (HL7) C1549696) =Intellectual Product =Identifier type;
| - 184. dorsal root ganglion
- [ganglion found on the posterior root of each spinal nerve, composed of the unipolar nerve cell bodies of the sensory neurons of the nerve. ( CSP )] (UMLS (CSP) C0017070) =Body Part, Organ, or Organ Component ;
=ganglion;
|
- 135. Donors of other specified organ or tissue
- [ ] (UMLS (ICD9CM) C0260790) =Population Group
| - 185. DORSAL ROOT INJURY
- [ ] (UMLS (ICD9CM) C1536686) Injury to dorsal nerve root;
=Injury or Poisoning; ;
|
- 136. Donors of unspecified organ or tissue
- (UMLS (ICD9CM) C0013019) =Finding
| - 186. Dorsal Thalamus
- (UMLS (NCI) C0699836) =Body Part, Organ, or Organ Component ;
|
- 137. Door
- [The entrance through which you enter or leave a room or building used as an element of an address. ( NCI )] (UMLS (NCI) C0557698) =Manufactured Object
| - 187. Dorsal Thoracic Artery
- (UMLS (NCI) C0933449) Thoracodorsal Artery;
=Body Part, Organ, or Organ Component |
- 138. DOPA decarboxylase
- [One of the AROMATIC-L-AMINO-ACID DECARBOXYLASES, this enzyme is responsible for the conversion of dopa to dopamine. It is of clinical importance in the treatment of Parkinson's disease. EC 4.1.1.28. ( MSH )] (UMLS (CSP) C0003806) =Amino Acid, Peptide, or Protein; Enzyme
| - 188. Dorsal [thoracic] spinal cord injury without evidence of spinal bone injury
- [ ] (UMLS (ICD9CM) C0161426) =Injury or Poisoning
|
- 139. DOPA decarboxylase inhibitor
- [ ] (UMLS (CSP) C0598272) =Organic Chemical; Pharmacologic Substance ;
| - 189. Dorsal-Ventral Pattern Formation
- [Dorsal-Ventral Pattern Formation is a developmental morphogenetic process that establishes the basic configuration of cellular organization necessary for further and accurate development of the spatial arrangement of embryonic tissue along the dorsal-ventral axis. ( NCI )] (UMLS (NCI) C1160449) =Organ or Tissue Function ;
|
- 140. DOPAC
- [A deaminated metabolite of LEVODOPA. ( MSH )] (UMLS (CSP) C0000376) =Organic Chemical; Biologically Active Substance ;
| - 190. Dorsalis Pedis Artery
- (UMLS (NCI) C0226492) =Body Part, Organ, or Organ Component
|
- 141. Dopaflex
- (UMLS (NCI) C1449995) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 191. Dorsalis Pedis Artery Branch
- (UMLS (NCI) C1282117) =Body Part, Organ, or Organ Component
|
- 142. Dopamet
- (UMLS (NCI) C0591404) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 192. Dorsomedial Nucleus of the Thalamus
- [The largest of the medial nuclei of the thalamus. It makes extensive connections with most of the other thalamic nuclei. ( MSH )] (UMLS (NCI) C0228329) =Body Part, Organ, or Organ Component
|
- 143. dopamine
- [one of the catecholamine neurotransmitters in the brain; it is derived from tyrosine and is the precursor to norepinephrine and epinephrine; dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement; dopamine receptors mediate its action. ( CSP )] (UMLS (CSP) C0013030) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =catecholamine;
Neurotransmitter;
Dopamine Agonist;
[AU100] SYMPATHOMIMETICS (ADRENERGICS) =DARPP;
DOPAMINE HYDROCHLORIDE;
| - 193. DORSOPATHIES
- [condition in which there is a deviation from or interruption of the normal structure or function of the spine. ( CSP )] (UMLS (ICD9CM) C0037933) =Disease or Syndrome ;
=Bone Diseases;
skeletal disorder =Sciatia;
scoliosis;
INFLAM SPONDYLOPATHY NOS;
spondylarthropathy;
Intervertebral Disk Displacement;
Platybasia;
JUV OSTEOCHONDROS SPINE;
Curvature of spine;
Intraspinal Neoplasm;
Spinal Osteophytosis;
Spinal Stenosis;
INFLAM SPONDYLOPATHY NOS;
Spondylolisthesis;
Pott's Disease;
Ossification of Posterior Longitudinal Ligament |
- 144. Dopamine Agonist
- [class of drugs and natural products which enhance dopaminergic function by increasing dopamine biosynthesis, decreasing dopamine degradation or reuptake, or interacting positively with dopamine receptors. ( CSP )] (UMLS (NCI) C0178601) =Pharmacologic Substance =neuropharmacologic agent;
neurotransmitter agonist;
Dopamine Receptor Interactions;
=apomorphine;
2-Bromo-alpha-ergocryptine;
cocaine;
dihydroxyphenylalanine;
dopamine;
PERGOLIDE;
FENOLDOPAM | - 194. Dorsum of the Tongue
- (UMLS (NCI) C0226952) =Body Part, Organ, or Organ Component
|
- 145. Dopamine Antagonist
- [class of drugs and natural products which inhibit dopaminergic function by decreasing dopamine biosynthesis, increasing dopamine degradation or reuptake, or interacting negatively with dopamine receptors. ( CSP )] (UMLS (NCI) C0242702) =Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =catecholamine inhibitor;
Dopamine Receptor Interactions =methylphenyltetrahydropyridine;
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone;
raclopride;
SCH 23390;
2,4,5-Trihydroxyphenethylamine | - 195. Dorsum/Dorsal
- (UMLS (HL7) C1550247) =Body Location or Region =Body Part;
|
- 146. dopamine hydroxylase inhibitor
- [any substance or agent which suppresses, prevents or opposes the action of dopamine hydroxylase which catalyzes the biosynthesis of norepinephrine from dopamine. ( CSP )] (UMLS (CSP) C0596457) =Pharmacologic Substance =oxidoreductase inhibitor;
| - 196. DORZOLAMIDE
- [An inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distributed throughout many cells and tissues, various carbonic anhydrases play important roles in mineral and metabolic homeostasis. (NCI04) ( NCI )] (UMLS (NCI) C0165590) =Organic Chemical; Pharmacologic Substance =sulfonamide;
Thiophenes;
[OP104] CARBONIC ANHYDRASE INHIBITORS, SYSTEMIC OPHTHALMIC;
=Dorzolamide Hydrochloride |
- 147. dopamine receptor
- [family of G protein-coupled receptors of two general classes: D1 (- A, -B) stimulation increases intracellular cAMP, whereas D2, D3, or D4 stimulation decreases cAMP, increases K+ flux, or decreases Ca++ flux. ( CSP )] (UMLS (CSP) C0034798) =Amino Acid, Peptide, or Protein; Receptor ;
=neurotransmitter receptor;
| - 197. Dorzolamide Hydrochloride
- [The hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distributed throughout many cells and tissues, various carbonic anhydrases play important roles in mineral and metabolic homeostasis. (NCI04) ( NCI )] (UMLS (NCI) C0771293) DORZOLAMIDE HYDROCHLORIDE PREPARATION;
=Organic Chemical; Pharmacologic Substance =DORZOLAMIDE;
=DORZOLAMIDE HYDROCHLORIDE 2 %;
|
- 148. Dopamine Receptor D1
- [Dopamine Receptor D1, encoded by the human DRD1 gene, is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. It regulates neuronal growth and development, mediates some behavioral responses, and modulates dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1367800) DRD1;
DRD1 Protein =Amino Acid, Peptide, or Protein; Receptor | - 198. DOSAG FAIL-SHOCK THERAPY
- [ ] (UMLS (ICD9CM) C0261548) =Injury or Poisoning
|
- 149. Dopamine Receptor D1 Gene
- [This gene is involved in the regulation of dopamine receptor transport and neuronal signal transduction pertaining to neuronal growth and development. ( NCI )] (UMLS (NCI) C1333250) DRD1;
DRD1 Gene;
=Gene or Genome ;
| - 199. Dosage Form
- [forms in which chemical products can be manufactured or administered. ( CSP )] (UMLS (NCI) C0013058) =Biomedical or Dental Material =DDS;
|
- 150. Dopamine Receptor D2 A1 Allele
- [Human DRD2 Gene at 11q23 encodes Dopamine Receptor D2, a G-protein coupled receptor that inhibits adenylyl cyclase activity. Missense mutation in DRD2 causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing results in two different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. Different alleles are associated with increased incidence of substance abuse. The A1 allele has been associated with alcoholism. (NCI) ( NCI )] (UMLS (NCI) C1333251) DRD2 1 Allele;
DRD2 A1 Allele;
=Gene or Genome ;
| - 200. Dosage problem
- [Proposed dosage instructions for therapy differ from standard practice. ( HL7V3.0 )] (UMLS (HL7) C1553548) =Intellectual Product =AdministrationDetectedIssueCode;
=High Dose Alert;
Low Dose Alert;
Dose-Interval Alert;
Dose-Duration Alert |
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