- 201. 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
- [metabolite of pentifylline (a preparation of theobromine and hexyl halide); used as a vasodilator. ( CSP )] (UMLS (NCI) C0030899) =Organic Chemical; Pharmacologic Substance ;
=theobromine;
Vasodilating Agent;
[CV900] CARDIOVASCULAR AGENTS, OTHER;
=PENTOXIFYLLINE 400 MG;
| - 251. 6-D-(2-naphthyl)alanyl-GnRH
- [A potent synthetic agonist of GONADOTROPIN-RELEASING HORMONE with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central PRECOCIOUS PUBERTY and ENDOMETRIOSIS. ( MSH )] (UMLS (NCI) C0064906) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=D-His-6-Pro-8-NEt-LHRH;
[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER =(6-D-(2-Naphthyl)alanine)LHRH Acetate;
|
- 202. 3,7-Dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
- [Vitamin A. It is essential for proper vision and healthy skin and mucous membranes. Retinol is being studied for cancer prevention; it belongs to the family of drugs called retinoids. ( NCI )] (UMLS (NCI) C0087161) =Organic Chemical; Pharmacologic Substance; Vitamin =Retinoic Acid Agent;
| - 252. 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig)
- [GRH/LHRH analog used to suppress circulating gonadotropin and sex steroid levels; USP lists as an antineoplastic. ( CSP )] (UMLS (NCI) C0085272) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine; Hormone =[AN000] ANTINEOPLASTICS;
D-His-6-Pro-8-NEt-LHRH;
peptide hormone analog;
[AN500] ANTINEOPLASTIC HORMONES =6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) Monoacetate |
- 203. 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid
- [A drug being studied for cancer prevention. It belongs to the family of drugs called retinoids. ( NCI )] (UMLS (NCI) C0281666) =Organic Chemical; Pharmacologic Substance; Vitamin =(All-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid;
[DE600] ANTINEOPLASTICS, TOPICAL =ALITRETINOIN 0.1 % | - 253. 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) Monoacetate
- [The acetate salt of a synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors. Continuous, prolonged administration of leuprolide in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. This agent reduces testosterone production to castration levels and may inhibit androgen receptor-positive tumor progression. ( NCI )] (UMLS (NCI) C0700596) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig);
=LEUPROLIDE ACETATE 11.25 MG;
LEUPROLIDE ACETATE 15 MG;
LEUPROLIDE ACETATE 22.5 MG;
LEUPROLIDE ACETATE 30 MG;
LEUPROLIDE ACETATE 65 MG;
LEUPROLIDE ACETATE 72 MG;
LEUPROLIDE ACETATE 7.5 MG;
LEUPROLIDE ACETATE 1 MG/0.2ML;
LEUPROLIDE ACETATE 3.75 MG |
- 204. 3-(((Dimethylamino)carbonyl)oxy)-1-methylpyridinium Bromide
- [The bromide salt form of pyridostigmine, a quaternary ammonium carbamate derivative and a acetylcholinesterase inhibitor. Pyridostigmine bromide binds reversibly to acetylcholinesterase active sites in the peripheral nervous system, thereby preventing the breakdown of acetylcholine. This leads to an accumulation of acetylcholine at cholinergic synapses and facilitates transmission of impulses across the neuromuscular junction. Mediated through muscarinic receptors, this agent increases contraction of bronchial and intestinal smooth muscle and the exocrine glands secretions, while it causes paralysis of the skeletal muscles mediated through nicotinic receptors . In addition, pyridostigmine is used as a reversible blocking agent to prevent organophosphates from binding to the acetylcholinesterase receptors and thereby protect the nervous system from the effects of nerve agents such as Soman. ( NCI )] (UMLS (NCI) C0034262) =Organic Chemical; Pharmacologic Substance ;
=Pyridinium Compounds;
PYRIDOSTIGMINE =PYRIDOSTIGMINE BROMIDE 180 MG;
PYRIDOSTIGMINE BROMIDE 5 MG/ML;
PYRIDOSTIGMINE BROMIDE 60 MG;
PYRIDOSTIGMINE BROMIDE 60 MG/5ML;
| - 254. 6-D-Tryptophan-, 4,4'Mmethylenebis(3-hydroxy-2-naphthalenecarboxylate) (Salt)
- [The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. (NCI04) ( NCI )] (UMLS (NCI) C1137102) Pamorelin;
Triptorelin Pamoate;
TRIPTORELIN PAMOATE UNIDENTIFIED;
TRIPTORELIN PAMOATE PREPARATION;
TRIPTORELIN PAMOATE UNIDENTIFIED =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =6-D-Tryptophan-LH-RH;
Unclassified Ingredients =TRIPTORELIN PAMOATE 11.25 MG |
- 205. 3-(2,5-Dihydroxyphenyl)-2-propenoic Acid Methyl Ester
- [A cell-permeable analog of erbstatin, a compound isolated from Streptomyces that inhibits the autophosphorylation of epidermal growth factor receptor. Erbstatin analogue competitively inhibits epidermal growth factor receptor-associated tyrosine kinase, inhibiting the activation of v-abl tyrosine kinase. In addition, this agent has induced apoptosis in mouse thymocytes and inhibits the G2/M phase of the cell cycle. (NCI) ( NCI )] (UMLS (NCI) C0083406) =Organic Chemical; Pharmacologic Substance
| - 255. 6-D-Tryptophan-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor (Swine)
- [A synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) ( NCI )] (UMLS (NCI) C0083220) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 206. 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Monohydrate
- [The sodium salt form of dicloxacillin, a broad-spectrum, semi-synthetic beta-lactam with bactericidal and beta-lactamase resistant activity. Dicloxacillin sodium binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0887422) DICLOXACILLIN SODIUM;
DICLOXACILLIN SODIUM PREPARATION =Organic Chemical; Antibiotic ;
=3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin;
=DICLOXACILLIN SODIUM 250 MG;
DICLOXACILLIN SODIUM 500 MG;
DICLOXACILLIN SODIUM 62.5 MG/5ML | - 256. 6-D-Tryptophan-LH-RH
- [A hormonal anticancer drug that belongs to the family of drugs called gonadotropin-releasing analogues. ( NCI )] (UMLS (NCI) C0077275) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =[AN500] ANTINEOPLASTIC HORMONES;
Unclassified Ingredients =6-D-Tryptophan-, 4,4'Mmethylenebis(3-hydroxy-2-naphthalenecarboxylate) (Salt) |
- 207. 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin
- [A broad-spectrum, semi-synthetic, beta-lactam, penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Dicloxacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0012093) =Organic Chemical; Antibiotic =CLOXACILLIN;
[AM053] PENICILLINASE-RESISTANT PENICILLINS =3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Monohydrate;
| - 257. 6-deoxy-3,5 di-O-methyl 6-(3-methyl-3-nitrosoureido)-alpha-D-glucofuranoside
- (UMLS (NCI) C0116847) =Organic Chemical; Pharmacologic Substance ;
|
- 208. 3-(2-Dimethylamino)ethylindol-4-ol Dihydrogen Phosphate
- [A tryptamine alkaloid, isolated from fungi of the genus Psilocybe with hallucinogenic, anxiolytic and psychoactive activities. Psilocybin is converted by phosphatases in vivo into the active compound psilocin. Psilocin exerts its effect by binding to and activating serotonin 2A (5-HT2A) and 1A (5-HT1A) receptors in the central nervous system, thereby mimicking the effects of serotonin. ( NCI )] (UMLS (NCI) C0033850) =Organic Chemical; Pharmacologic Substance
| - 258. 6-DIAZO-5-OXO-L-NORLEUCINE
- [An antibiotic isolated from Streptomyces with potential antineoplastic activity. Diazooxonorleucine inhibits several glutamine-dependent biosynthetic pathways including the synthesis of D-glucosamine phosphate, purines and pyrimidines. As an L-glutamine antagonist, diazooxonorleucine inhibits phosphate-activated glutaminase, thereby interfering with glutamine metabolism, ultimately depleting cells of this essential amino acid and reducing the capacity to proliferate. Another mechanism of action including inhibition of glycoprotein, gamma-guanosine triphosphatease, DNA and RNA synthesis has been proposed. ( NCI )] (UMLS (NCI) C0012020) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 209. 3-Deazaguanine
- [A purine nucleoside analogue with antineoplastic and antiviral activity. By replacing guanine, dezaguanine incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. (NCI) ( NCI )] (UMLS (NCI) C0047332) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 259. 6-Dibromodideoxydulcitol
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0026252) =Carbohydrate; Pharmacologic Substance ;
|
- 210. 30 day report
- (UMLS (HL7) C1546919) =Temporal Concept =Report timing;
| - 260. 6-[(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-Pyridinecarboxylic Acid, Ethyl Ester
- [A synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. (NCI04) ( NCI )] (UMLS (NCI) C0288792) =Organic Chemical; Pharmacologic Substance ;
=Nicotinic Acids;
[DE752] ANTIACNE AGENTS, TOPICAL =TAZAROTENE 0.1 %;
TAZAROTENE 0.05 % |
- 211. 30d
- [Mandibular right first molar distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552110) =Body Part, Organ, or Organ Component =Permanent dentition;
| - 261. 63-Desulfohirudin(Hirudo medicinalis isoform HV1)
- [A synthetic recombinant form of the naturally occurring hirudin, the anticoagulant substance found in leech. Desirudin is a selective and almost irreversible inhibitor of thrombin, both free and clot-bound, by blocking its active site. This anticoagulant agent has no effect on other components of the hemostatic system. Desirudin is particularly used to prevent deep vein thrombosis in patients undergoing hip and knee replacement surgery. ( NCI )] (UMLS (NCI) C0378366) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 212. 31d
- [Mandibular right second molar distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552112) =Body Part, Organ, or Organ Component =Permanent dentition;
| - 262. 7 day report
- (UMLS (HL7) C1546921) =Temporal Concept =Report timing;
|
- 213. 32d
- [Mandibular right third molar distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552114) =Body Part, Organ, or Organ Component =Permanent dentition;
| - 263. 7 days
- (UMLS (HL7) C1547085) =Temporal Concept =Time delay post challenge;
|
- 214. 3D
- [3-D. A graphic display of depth, width, and height. ( NCI )] (UMLS (NCI) C0450363) =Spatial Concept ;
| - 264. 7,8-Didehydro-4,5-epoxy- 3-methoxy-17-methyl-(5a ,6a)-Morphinan-6-ol Sulfate (2:1)
- [The sulfate salt form of codeine, a naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activity. Codeine sulfate mimics the actions of opioids by binding to the opioid receptors at many sites within the central nervous system (CNS). Stimulation of the mu-subtype opioid receptor stimulates the exchange of GTP for GDP on the G-protein complex and subsequently inhibits adenylate cyclase. This results in a decrease in intracellular cAMP and leads to a reduction in the release of neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline. The analgesic effect of codeine sulfate is likely due to its metabolite morphine, which induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels and blocks the opening of N-type voltage-gated calcium channels, thereby resulting in hyperpolarization and reduced neuronal excitability. ( NCI )] (UMLS (NCI) C0304352) =Organic Chemical; Pharmacologic Substance =codeine;
=CODEINE SULFATE 10 MG;
CODEINE SULFATE 30 MG;
CODEINE SULFATE 10 MG/5ML;
CODEINE SULFATE 60 MG;
CODEINE SULFATE 15 MG |
- 215. 3D image
- [ ] (UMLS (CSP) C1253948) three dimensional image =Manufactured Object
| - 265. 7,8-Dihydro-8-Oxoguanine Triphosphatase
- [Human 7,8-dihydro-8-oxoguanine triphosphatase protein (197 aa, 23 kD - unprocessed precursor) is encoded by the nudix (nucleoside diphosphate linked moiety X)-type motif 1 gene (NUDT1). Isoforms of this soluble protein are localized to both the cytoplasm and mitochondria of the cell. It catalyzes the hydrolysis of 8-oxo-dGTP to yield 8-oxo-dGMP and diphosphate. Misincorporation of 8-oxo-dGTP into DNA can result in A:T to C:G transversion mutations. Therefore, this enzyme is considered to be antimutagenic. ( NCI )] (UMLS (NCI) C0210507) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 216. 3D imaging
- [Technique to produce 3D images to provide the ability to visualize important structures in great detail. Traditionally CT and MRI scans produced static output on film. To produce 3D images, many scans are made, and then combined by computers to produce a 3D model, which can then be manipulated by the physician. 3D ultrasounds are produced using a somewhat similar technique. ( NCI )] (UMLS (CSP) C0887832) 3-D Imaging;
Medical Imaging, Three Dimensional;
Three Dimensional Imaging =Diagnostic Procedure | - 266. 7-(D-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-caboxylic Acid
- [Cephalosporin antibiotic, partly plasma-bound, that is effective against gram-negative and gram-positive organisms. ( MSH )] (UMLS (NCI) C0007737) =Organic Chemical; Antibiotic =Cephacetrile;
[AM101] CEPHALOSPORINS, 1ST GENERATION =7-(alpha-(4-Pyridylthio)acetamido)cephalosporanic acid sodium salt;
|
- 217. 3D-CRT
- [A process by which a dose of radiation is automatically shaped to closely conform to the entire volume of the tumor, so that surrounding normal tissue is spared and treatment toxicity is decreased. ( NCI )] (UMLS (NCI) C0600521) =Therapeutic or Preventive Procedure ;
| - 267. 9,10-Dihydroergotamine Mesylate
- [An ergot derivative with agonistic activity for alpha-adrenergic, serotonergic, and dopaminergic receptors. Dihydroergotamine mesylate most likely relieves migraine headaches by binding to and stimulating the 5-HT1D receptor subtype, thereby causing constriction of cerebral blood vessels. However, it has also been proposed that dihydroergotamine mesylate acts upon 5-HT1D receptors on sensory nerve endings of the trigeminal system, thereby decreasing the release of pro-inflammatory neuropeptide release. ( NCI )] (UMLS (NCI) C0700532) =Organic Chemical; Pharmacologic Substance =DIHYDROERGOTAMINE;
=DIHYDROERGOTAMINE MESYLATE 1 MG/ML;
DIHYDROERGOTAMINE MESYLATE 4 MG/ML;
|
- 218. 4',7-Dihydroxyisoflavone
- [An isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties. (NCI) ( NCI )] (UMLS (NCI) C0057090) =Organic Chemical; Vitamin ;
| - 268. D
- [Maxillary right lateral primary incisor ( HL7V3.0 )] (UMLS (HL7) C0227086) =Body Part, Organ, or Organ Component =Primary dentition;
|
- 219. 4'-Demethylepipodophyllotoxin 9-[4,6-O-ethylidene-beta-D-glucopyranoside
- [glucopyranosyl substituted naphthalene derived from podophyllin; mutagen and immunosuppressant used in combination antineoplastic therapy for several human malignancies. ( CSP )] (UMLS (NCI) C0015133) =Carbohydrate; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Glucosides;
[IM600] IMMUNE SUPPRESSANTS;
Mutagen;
Mayapple Extract;
PODOFILOX =Etoposide Phosphate;
ETOPOSIDE 20 MG/ML;
ETOPOSIDE 50 MG;
ETOPOSIDE 100 MG;
ETOPOSIDE 200 MG;
ETOPOSIDE 500 MG;
| - 269. d
- [The time for Earth to make a complete rotation on its axis; ordinarily divided into twenty-four hours. This also refers to a specific day. (NCI) ( NCI )] (UMLS (NCI) C0439228) =Temporal Concept =UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens |
- 220. 4'-Deoxy-20',20'-difluoro-C'-norvincaleukoblastine
- [A novel fluorinated Vinca alkaloid with antiangiogenic and antitumor activities. Although the exact mechanism of the mitotic block is not clear, vinflunine could induce cell cycle arrest at G2/M phase, and cause a concentration-dependent reduction of the microtubular network of interphase cells, thereby leading to apoptosis. This agent appears to function as an inhibitor of tubulin assembly, while exhibiting quantitatively different behaviors and showing lower binding capacity than the classic Vinca alkaloids. Furthermore, vinflunine exhibits improved pharmacokinetic properties, including increased lipophilicity, and is more resistant to metabolic degradation. ( NCI )] (UMLS (NCI) C0672663) =Organic Chemical; Pharmacologic Substance ;
| - 270. D & C and Conization
- (UMLS (HL7) C1548844) =Health Care Activity =Consent Type;
|
- 221. 4'-Deoxy-4'-Iododoxorubicin
- [A substance that is being studied as a treatment for cancer, and for primary systemic amyloidosis (a disease in which proteins are deposited in specific organs). It belongs to the family of drugs called anthracycline analogues. ( NCI )] (UMLS (NCI) C0047758) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 271. D & C FOR PREG TERMINAT
- [ ] (UMLS (ICD9CM) C0195641) =Therapeutic or Preventive Procedure
|
- 222. 4'-Deoxyadriamycin
- [A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin. Esorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent antibiotic doxorubicin, but may cause severe myelosuppression. (NCI04) ( NCI )] (UMLS (NCI) C0047760) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 272. D & C NEC
- [ ] (UMLS (ICD9CM) C0376038) =Therapeutic or Preventive Procedure
|
- 223. 4'-Deoxyadriamycin Hydrochloride
- (UMLS (NCI) C0955070) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 273. D & C POST DELIVERY
- [ ] (UMLS (ICD9CM) C0177204) =Therapeutic or Preventive Procedure
|
- 224. 4'-Deoxyepivincristine
- [A vinca alkaloid compound and semi-synthetic vincristine derivative with antineoplastic activity. Vinepidine binds to and stabilizes tubulin, thereby preventing tubulin polymerization and depolymerization, which result in microtubule assembly and disassembly, respectively. Treated cells are unable to complete mitosis process and are arrested in the metaphase, thereby leading to an inhibition of cell growth. ( NCI )] (UMLS (NCI) C0078255) =Organic Chemical; Pharmacologic Substance ;
| - 274. D 24851
- [A synthetic cytotoxic small molecule that binds to tubulin. Bound to tubulin, D 24851 inhibits tubulin polymerization, cell cycle progression at the G2/M phase and, consequently, tumor cell growth. This agent has been shown to be active against multi-drug resistant tumors. (NCI04) ( NCI )] (UMLS (NCI) C0963638) =Organic Chemical; Pharmacologic Substance ;
|
- 225. 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]
- [A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. ( MSH )] (UMLS (NCI) C0028347) =Organic Chemical; Pharmacologic Substance ;
=catechol;
=MASOPROCOL;
| - 275. D amphetamine
- [d-form of amphetamine; it is a central nervous system stimulant and a sympathomimetic; it has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children; dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase; it is also a drug of abuse and a psychotomimetic. ( CSP )] (UMLS (CSP) C0011812) =Organic Chemical; Pharmacologic Substance ;
=Amfetamine;
[CN801] AMPHETAMINES =(S)-alpha-Methylbenzeneethanamine Sulfate;
Dextroamphetamine Saccharate;
AMPHETAMINE/DEXTROAMPHETAMINE RESIN COMPLEX;
DEXTROAMPHETAMINE ADIPATE;
(S)-alpha-Methylbenzeneethanamine Sulfate;
Dextroamphetamine Saccharate;
DEXTROAMPHETAMINE 6.25 MG;
DEXTROAMPHETAMINE ADIPATE PREPARATION;
|
- 226. 4,4'-(Dimethylamino)benzophenone
- [A white to green colored leaflet material that emits toxic fumes of nitrogen oxides when heated to decomposition. Michler's ketone is used as a chemical intermediate in making dyes and pigments, particularly auramine derivatives, for dyeing paper, textiles, and leather. Exposure to Michler's ketone affects the central nervous system. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0066505) =Organic Chemical; Hazardous or Poisonous Substance
| - 276. D and C
- [(dye-LAY-shun and kyoo-reh-TAHZH) D&C. A minor operation in which the cervix is expanded enough (dilation) to permit the cervical canal and uterine lining to be scraped with a spoon-shaped instrument called a curette (curettage). ( NCI )] (UMLS (NCI) C0012358) =Therapeutic or Preventive Procedure
|
- 227. 4,4'-DADPE
- [A colorless, odorless, combustible aromatic amine that emits toxic fumes of nitrogen oxides when heated to decomposition. 4,4'-Oxydianiline is used in industry in the manufacture of polyimide and polyester resins. Exposure to this substance is irritating to the eyes, skin and respiratory-tract. 4,4'-Oxydianiline is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0057642) =Organic Chemical; Pharmacologic Substance ;
| - 277. D Cell
- [Cells found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. (MeSH) ( NCI )] (UMLS (NCI) C0524984) =Cell ;
|
- 228. 4,4'-Diaminodiphenylsulfide
- [A brown to violet colored solid aromatic amine that emits toxic fumes of nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen and sulfur oxides when heated to decomposition. 4,4'-Thiodianiline is primarily used as a chemical intermediate in the production of certain dyes. Exposure to this substance is irritating to the respiratory tract and can result in methemoglobinemia causing headache, dizziness, weakness and can lead to shortness of breath, collapse and even death. 4,4'-Thiodianiline is a possible mutagen and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0047830) =Organic Chemical; Pharmacologic Substance ;
| - 278. D factor
- [ ] (UMLS (CSP) C0057027) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
|
- 229. 4,4'-Diamonophenyl
- [A grayish-red, yellowish or white colored, very toxic, crystalline aromatic amine that darkens when exposed to air and light. Benzidine has been widely used for the detection of blood and as a reagent in the manufacture of dyes. Ingestion of benzidine causes cyanosis, headache, mental confusion, nausea and vomiting. Its use is now limited because of strong association between exposure to benzidine and an increased risk of bladder cancer in humans. (NCI05) ( NCI )] (UMLS (NCI) C0005047) =Organic Chemical; Hazardous or Poisonous Substance
| - 279. D glucitol
- [six-carbon sugar alcohol with about half the sweetness of sucrose; occurs naturally and is also produced synthetically from glucose. ( CSP )] (UMLS (CSP) C0037688) =Carbohydrate; Pharmacologic Substance ;
=sugar alcohol;
sweetening agent;
[IR100] IRRIGATION SOLUTIONS;
[PH000] PHARMACEUTICAL AIDS / REAGENTS =ISOSORBIDE;
MEGLUMINE;
SORBITOL SOLUTION;
ARTIFICIAL SALIVA;
IBERET 500 LIQUID;
LUBRIDERM LOTION,SCENTED;
Clemastine 0.1 MG/ML Syrup;
Benzocaine 0.075 MG/MG Oral Gel;
Urea 0.1 MG/MG Topical Ointment;
SORBITOL SOLUTION;
Chlorpheniramine 0.2 MG/ML / Dextromethorphan More… |
- 230. 4,4'-Dichloro-2,2'-methylenediphenol
- [A nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ingredient in antimicrobial soaps and shampoos. This agent probably acts by increasing the clearing of intestinal contents, thereby eradicating tapeworm infections from the intestines. ( NCI )] (UMLS (NCI) C0012082) =Organic Chemical; Pharmacologic Substance
| - 280. D lactate dehydrogenase
- [ ] (UMLS (CSP) C0112125) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 231. 4,4'-Dichloro-3-(trifluoromethyl)-carbanilide
- [A synthetic, carbanilide compound with antiseptic activity. Cloflucarban is used as disinfectant and is found in antimicrobial soaps and deodorants. ( NCI )] (UMLS (NCI) C0055912) =Organic Chemical; Pharmacologic Substance ;
| - 281. D segment gene
- [ ] (UMLS (CSP) C0598660) =Gene or Genome
|
- 232. 4,5-Diphenyl-2-oxazolepropionic Acid
- [A nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04) ( NCI )] (UMLS (NCI) C0069739) =Organic Chemical; Pharmacologic Substance =Propionic Acids;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC =OXAPROZIN 600 MG;
| - 282. D(1B) Dopamine Receptor
- [Dopamine Receptor D5, encoded by the human DRD5 gene, is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. This receptor complexes selectively with GABA-A ligand-gated channel through the direct binding of its carboxy-terminal domain with the second intracellular loop of the GABA-A gamma-2 (short) receptor subunit. This physical association enables mutual inhibitory functional interactions between these receptor systems. Pseudogenes related to this gene reside on chromosomes 1 and 2. Defects in DRD5 are a cause of blepharospasm, a primary focal dystonia affecting the orbicularis oculi muscles, usually beginning in middle age. (From LocusLink, Swiss-Prot, OMIM and NCI) ( NCI )] (UMLS (NCI) C0114836) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 233. 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one
- (UMLS (NCI) C0064041) =Organic Chemical
| - 283. D(DHAD)TH
- (UMLS (NCI) C0279349) =Therapeutic or Preventive Procedure
|
- 234. 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
- [A sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension. ( NCI )] (UMLS (NCI) C0252643) =Organic Chemical; Pharmacologic Substance =[CV900] CARDIOVASCULAR AGENTS, OTHER;
Unclassified Ingredients =BOSENTAN 125 MG;
BOSENTAN 62.5 MG;
| - 284. D(DHAD)V
- (UMLS (NCI) C0279683) =Therapeutic or Preventive Procedure
|
- 235. 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide
- [A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. ( NCI )] (UMLS (NCI) C0039644) =Organic Chemical; Antibiotic ;
=[GA303] H.PYLORI AGENTS;
[AM250] TETRACYCLINES =(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride;
TETRACYCLINE 125 MG/5ML;
TETRACYCLINE 500 MG | - 285. d,l-alpha-Tocopherol Acetate
- (UMLS (NCI) C0994472) dl-.alpha.-Tocopheryl acetate;
dl-alpha tocopheryl acetate;
dl-Alpha-Tocopheryl Acetate;
TOCOPHERYL ACETATE,DL-ALPHA;
TOCOPHERYL ACETATE,DL-ALPHA PREPARATION =Lipid; Pharmacologic Substance; Vitamin =(+/-)-alpha-Tocopherol;
=CARRINGTON FOOT CREAM;
ULTRACAL TUBE-FEEDING LIQUID;
dl-alpha tocopheryl acetate 200 MG/ML;
TOCOPHERYL ACETATE,DL-ALPHA 0 NS;
TOCOPHERYL ACETATE,DL-ALPHA 11 MG;
TOCOPHERYL ACETATE,DL-ALPHA 15 MG;
TOCOPHERYL ACETATE,DL-ALPHA 15 UNT;
TOCOPHERYL ACETATE,DL-ALPHA 2 UNT/ML;
TOCOPHERYL ACETATE,DL-ALPHA 30 MG;
TOCOPHERYL ACETATE,DL-ALPHA 30 UNT;
TOCOPHERYL ACETATE,DL-ALPHA 400 UNT;
TOCOPHERYL ACETATE,DL-ALPHA 5 MG;
TOCOPHERYL ACETATE,DL-ALPHA 5 UNT;
TOCOPHERYL ACETATE,DL-ALPHA 50 MG;
TOCOPHERYL ACETATE,DL-ALPHA 7.7 UNT;
|
- 236. 4-dedimethylamino sancycline
- [An anticancer drug that may stop tumor growth by preventing the growth of new blood vessels into a solid tumor. ( NCI )] (UMLS (NCI) C0763138) 4-Dimethlyamino Sancycline;
4-Dimethlyaminosancycline;
6-deoxy, 6-demethyl, 4-de-dimethylamino tetracycline;
6-deoxy-6-demethyl-4-dedimethylaminotetracycline;
CMT-3;
COL 3;
COL-3 =Organic Chemical; Pharmacologic Substance | - 286. D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide
- [An alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing. ( NCI )] (UMLS (NCI) C0057610) =Organic Chemical; Pharmacologic Substance; Vitamin =[VT107] PANTOTHENIC ACID;
D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide;
[GA900] GASTRIC MEDICATIONS, OTHER;
TO BE DELETED INGREDIENT PREPARATIONS =D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide;
dl-PANTHENOL;
D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide;
DEXPANTHENOL 250 MG/ML;
DEXPANTHENOL 50 MG;
DEXPANTHENOL 10 MG/ML;
DEXPANTHENOL 1 MG;
DEXPANTHENOL 10 MG/45ML;
DEXPANTHENOL 15 MG/ML;
DEXPANTHENOL 2 MG/ML;
DEXPANTHENOL 2.5 MG/5ML;
DEXPANTHENOL 25 MG;
DEXPANTHENOL 5 MG;
DEXPANTHENOL 5 MG/30ML;
DEXPANTHENOL 5.25 MG;
DEXPANTHENOL 6 MG/ML;
DEXPANTHENOL 15 MG/5ML;
D-PANTHENOL 6 MG/ML |
- 237. 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
- [A tertiary amine possessing antimuscarinic and antispasmodic properties. Oxybutynin blocks muscarinic receptors in smooth muscle, hence inhibiting acetylcholine binding and subsequent reduction of involuntary muscle contractions. Oxybutynin is used to reduce bladder contractions by relaxing bladder smooth muscle. ( NCI )] (UMLS (NCI) C0069805) =Organic Chemical; Pharmacologic Substance ;
=Mandelic Acids;
[GU201] ANTISPASMODICS, URINARY =OXYBUTYNIN CHLORIDE;
OXYBUTYNIN 3.9 MG;
| - 287. D-18506
- (UMLS (NCI) C0111934) =Organophosphorus Compound; Pharmacologic Substance ;
|
- 238. 4-Dimethylaminoazobenzene
- [A yellow, crystalline solid compound. 4-Dimethylaminoazobenzene was used as a dye for coloring polishes, wax products, polystyrene and soap, and was also used as a pH indicator, but is no longer used or produced in the United States. Exposure to this substance causes dermatitis. 4-dimethylaminoazobenzene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0012411) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 288. D-19466
- (UMLS (NCI) C0082183) =Organic Chemical; Pharmacologic Substance ;
|
- 239. 4-[2-[4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
- [A synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. (NCI04) ( NCI )] (UMLS (NCI) C1257385) 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide;
Lonafarnib;
=Organic Chemical; Pharmacologic Substance ;
| - 289. D-19575
- (UMLS (NCI) C0294271) =Organophosphorus Compound; Pharmacologic Substance ;
|
- 240. 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-cytidine
- [An anticancer drug that belongs to the family of drugs called antimetabolites. ( NCI )] (UMLS (NCI) C0671970) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
deoxycytidine =CAPECITABINE 150 MG;
CAPECITABINE 500 MG | - 290. D-20761
- [A synthetic luteinizing hormone-releasing hormone (LH-RH) antagonist that suppresses LH and sex steroid levels. ( NCI )] (UMLS (NCI) C0684303) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone
|
- 241. 5'-Deoxy-5-fluorouridine
- [A fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand. ( NCI )] (UMLS (NCI) C0048808) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 291. D-Alanine Metabolism
- [The chemical reactions and pathways involving D-alanine, the dextrorotatory isomer of the amino acid alanine. [GOC:ai] ( GO )] (UMLS (NCI) C1156808) D-Alanine Metabolism Pathway;
=Molecular Function |
- 242. 5,5-Diphenyl-2,4-imidazolidinedione
- [anticonvulsant used in a wide variety of seizures; also an anti-arrhythmic and a muscle relaxant. ( CSP )] (UMLS (NCI) C0031507) =Organic Chemical; Pharmacologic Substance =[CN400] ANTICONVULSANTS;
hydantoin =5,5-Diphenyl-2,4-imidazolidinedione, Monosodium Salt;
Fosphenytoin;
PHENYTOIN SODIUM EXTENDED;
5,5-Diphenyl-2,4-imidazolidinedione, Monosodium Salt;
PHENYTOIN SODIUM EXTENDED;
PHENYTOIN 125 MG/5ML;
PHENYTOIN 50 MG;
PHENYTOIN 30 MG/5ML;
PHENYTOIN 100 MG | - 292. d-Alpha Tocopheryl Polyethylene Glycol 1000 Succinate
- [A water soluble, amphipathic preparation of d-alpha-tocopherol succinate coupled, through a succinate linker, to polyethylene glycol (PEG) 1000. Due to its amphipathic property, tocophersolan is easily taken up into enterocytes where fat soluble d-alpha-tocopherol is released after hydrolysis. This preparation displays an enhanced absorption of d-alpha tocopherol compared to the administration of free d-alpha-tocopherol. In addition, tocophersolan may also enhance the absorption of water-insoluble agents and other fat-soluble vitamins. This agent has the ability to form its own micelles due to its amphipathic nature, thereby allowing absorption in absence of bile acids. ( NCI )] (UMLS (NCI) C0606070) =Organic Chemical ;
|
- 243. 5,5-Diphenyl-2,4-imidazolidinedione, Monosodium Salt
- [The sodium salt form of phenytoin, a hydantoin derivate and non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin sodium promotes sodium efflux from neurons located in the motor cortex, thereby stabilizing the neuron and inhibiting synaptic transmission. This leads to a reduction in posttetanic potentiation at synapses, an inhibition of repetitive firing of action potentials and ultimately inhibits the spread of seizure activity. ( NCI )] (UMLS (NCI) C0237417) =Organic Chemical; Pharmacologic Substance =5,5-Diphenyl-2,4-imidazolidinedione;
=PHENYTOIN SODIUM 100 MG;
PHENYTOIN SODIUM 125 MG/5ML;
PHENYTOIN SODIUM 50 MG/ML;
PHENYTOIN SODIUM 30 MG;
PHENYTOIN SODIUM 300 MG;
PHENYTOIN SODIUM 200 MG;
| - 293. D-Gluconic Acid, delta-Lactone
- [A naturally occurring polyhydroxy acid (PHA) with metal chelating, moisturizing and antioxidant activity. Gluconolactone can be produced by enzymatic oxidation of D-glucose oxidation. Its ability in free radicals scavenging accounts for its antioxidant property. It is used in cosmetic product and as a coagulant in tofu processing. (NCI05) ( NCI )] (UMLS (NCI) C0061387) =Carbohydrate; Pharmacologic Substance ;
=Unclassified Ingredients;
Inactive Ingredient Preparations =LUBRICATING JELLY,TOP;
GLUCONO-DELTA-LACTONE 0.198 GM/100ML |
- 244. 5,6-Dimethylxanthenone-4-Acetic Acid
- [An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. ( NCI )] (UMLS (NCI) C0081181) =Organic Chemical; Pharmacologic Substance
| - 294. D-Gluconic Acid, Monosodium Salt
- [The sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions. ( NCI )] (UMLS (NCI) C0142853) =Organic Chemical; Pharmacologic Substance ;
=[TN404] SODIUM;
Inactive Ingredient Preparations =SODIUM GLUCONATE 502 MG;
SODIUM GLUCONATE 0.5 GM;
SODIUM GLUCONATE 1.1 GM;
SODIUM GLUCONATE 500 MG/100ML;
SODIUM GLUCONATE 502 MG/100ML;
SODIUM GLUCONATE 461 MG/100ML;
|
- 245. 5,7-Dichloro-8-hydroxyquinoline
- [A synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epidermis, thereby reducing excessive scaling associated with dandruff or seborrheic dermatitis of the scalp, including psoriasis and eczema. ( NCI )] (UMLS (NCI) C0055461) =Organic Chemical; Pharmacologic Substance =Chloroquinolinols;
[DE400] SOAPS/SHAMPOOS/SOAP-FREE CLEANSERS =CHLOROXINE 2 % | - 295. D-His-6-Pro-8-NEt-LHRH
- [LH-RH. A hormone that stimulates the production of sex hormones in men and women. ( NCI )] (UMLS (NCI) C0023610) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine; Hormone =[HS400] GONADOTROPINS;
Hypothalamic Hormone;
neuropeptide;
oligopeptide =6-D-(2-naphthyl)alanyl-GnRH;
ganirelix;
6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig);
6-[O-(1,1-Dimethylethyl)-D-serine]-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide;
GONADORELIN ACETATE;
GONADORELIN HYDROCHLORIDE;
GONADORELIN ACETATE;
GONADORELIN HYDROCHLORIDE;
|
- 246. 5-(((2,5-Dihydroxyphenyl)methyl)((2-hydroxyphenyl)methyl)amino)-2-hydroxy Benzoic Acid
- [A compound isolated from strains of Streptomyces griseolavendus that may exert antitumor activity by inhibition of protein tyrosine kinase and tubulin polymerization. (NCI) ( NCI )] (UMLS (NCI) C0064695) =Organic Chemical; Pharmacologic Substance ;
| - 296. D-Mannitol
- [six-carbon sugar alcohol formed by reduction of mannose or fructose and widely distributed in plants and fungi. ( CSP )] (UMLS (NCI) C0024730) =Carbohydrate; Pharmacologic Substance ;
=sugar alcohol;
sweetening agent;
[IR100] IRRIGATION SOLUTIONS;
[CV709] DIURETICS, OTHER =MANNITOL HEXANITRATE;
AL OH 400MG/MG OH 400MG/SIMETHICONE 30MG TAB,CHEWABLE;
Aluminum Hydroxide 160 MG / magnesium carbonate 105 MG Chewable Tablet;
Ascorbic Acid 300 MG / Ferrous fumarate 134 MG Chewable Tablet;
CAFFEINE 100 MG Oral (systemic) tablet;
Doxycycline 10 MG/ML Injectable Solution;
Menthol 0.0012 MG/MG / phenol 0.0072 MG/MG Lozenge;
Menthol 0.0012 MG/MG / phenol 0.0145 MG/MG Lozenge;
ULTRA-KLENZ,WOUND CLEANSER;
MANNITOL 100 MG/ML;
MANNITOL 150 MG/ML;
MANNITOL 200 MG/ML;
MANNITOL 250 MG/ML;
MANNITOL 0.54 GM/100ML;
MANNITOL 50 MG/ML;
MANNITOL 375 MG;
MANNITOL 400 MG;
MANNITOL 50 MG;
MANNITOL 10 MG;
MANNITOL 10 MG/ML;
MANNITOL 100 MG;
MANNITOL 200 MG;
MANNITOL 40;
MANNITOL 40 MG;
MANNITOL 5 %;
MANNITOL 5 MG;
MANNITOL 500 MG;
MANNITOL 61.3 MG/ML;
MANNITOL 75 MG;
MANNITOL 750 MG;
MANNITOL 80 MG;
MANNITOL 150 MG;
MANNITOL 1.5 GM/VIL |
- 247. 5-((3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-yl)phenyl)pyridine
- [A nonpeptide angiotensin II receptor antagonist with antihypertensive activity. Forasartan selectively competes with angiotensin II for the binding of the angiotensin II (AT1) receptor subtype 1 in vascular smooth muscle, thereby blocking angiotensin II-mediated vasoconstriction resulting in vascular dilatation. In addition, the antagonistic effect on AT1 in the adrenal gland, prevents angiotensin II-induced stimulation of aldosterone synthesis and secretion by the adrenal cortex. This blocks the effects of aldosterone leading to an increase in sodium excretion and water and eventually a reduction in plasma volume and blood pressure. ( NCI )] (UMLS (NCI) C0250070) =Organic Chemical; Pharmacologic Substance ;
| - 297. D-Phenylalanine
- [The synthetic dextro isomer of phenylalanine, an essential amino acid with anti-depressant and analgesic activity. D-Phenylalanine is converted into tyrosine and tyrosine in turn is converted into L-dopa, norepinephrine, and epinephrine, three key neurotransmitters. As a result this agent is associated with elevated levels of the neurotransmitters dopamine and norepinephrine in the brain, which may alleviate symptoms of depression. In addition, as an inhibitor of enkephalinase, which metabolizes endorphins, D-phenylalanine may be used to treat chronic pain through blocking the break down of endorphins (natural pain killers). ( NCI )] (UMLS (NCI) C0771172) PHENYLALANINE,D-;
=Amino Acid, Peptide, or Protein; Pharmacologic Substance |
- 248. 5-(1,2-Dithiolan-3-yl)pentanoic Acid
- [A naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with potential chemopreventive and protective properties. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage, regenerates endogenous antioxidants, including vitamin C, E and glutathione. This antioxidant also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids. ( NCI )] (UMLS (NCI) C0023791) =Organic Chemical; Pharmacologic Substance; Vitamin
| - 298. D-Ser(bu(t))(6)azgly(10)-LHRH Acetate
- [The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) ( NCI )] (UMLS (NCI) C0700476) =Amino Acid, Peptide, or Protein; Pharmacologic Substance =6-[O-(1,1-Dimethylethyl)-D-serine]-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide;
=GOSERELIN ACETATE 10.8 MG;
GOSERELIN ACETATE 3.6 MG |
- 249. 5-[[4-[4(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl\-2,4-thiazolidinedione
- [A drug used in diabetes treatment that is being studied for its effect on reducing the risk of cancer cell growth in fat tissue. ( NCI )] (UMLS (NCI) C0245514) =Organic Chemical; Pharmacologic Substance ;
=Chromans;
antihyperglycemic;
thiazole;
Unclassified Ingredient Preparations | - 299. D.C.
- [The area in the United States comprised of a 68 square mile area northeast of the Potomac River donated by the state of Maryland. The District of Columbia, also known as D.C., is not a state, nor is it part of any state. It is a "federal district" established by the US Constitution as the seat of government. The district is occupied entirely by the city of Washington. ( NCI )] (UMLS (NCI) C0012764) =Geographic Area ;
|
- 250. 6-(2,2-Dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid
- [A semi-synthetic penicillin compound with bactericidal properties. Hetacillin is a prodrug that is converted to ampicillin. Ampicillin binds to inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs, including transpeptidases, carboxypeptidases, and endopeptidases, participate in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. This results in the weakening of the bacterial cell wall and eventually causes cell lysis. (NCI05) ( NCI )] (UMLS (NCI) C0062587) =Organic Chemical; Antibiotic ;
| - 300. D/C
- [To stop or end, permanently or temporarily. ( NCI )] (UMLS (NCI) C1444662) dc;
disc;
Discontinuation;
Discontinue;
Discontinued;
Discontinuous =Finding ;
|
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