UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
B B B0 B1 B4 B7 B8 BA BB BC BD BE BF BG BH BI BK BL BM BN BO BP BR BS BT BU BV BW BX BY BZ
BIA BIB BIC BID BIE BIG BIL BIM BIN BIO BIP BIR BIS BIT BIV

(1,1'-Biphenyl)-3-carboxylic Acid, 2',4'-difluoro-4-hydroxy-

[A difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. Diflunisal competitively inhibits both cyclooxygenase (COX) -1 and -2, with higher affinity for COX-1, and subsequently blocks the conversion of arachidonic acid to prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. Diflunisal differs from other salicylates, in that it is not metabolized to salicylic acid, hence it has a longer half-life. ( NCI )]
UMLS (NCI) C0012228
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: Salicylic Acids
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC
Relation/CHD: DIFLUNISAL 500 MG
DIFLUNISAL 250 MG

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