(o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate
[The tosylate salt form of bretylium, a quaternary ammonium salt and non-selective adrenergic neuronal blocking agent with anti-arrhythmic properties. Bretylium tosylate is selectively taken up into peripheral nerve terminals and initially causes a release of norepinephrine from sympathetic nerve endings, thereby causing a sympathomimetic effect. This is followed by a prolonged anti-adrenergic action which prevents further discharge of neurotransmitter from sympathetic nerve endings. Its myocardial effects include a prolongation of action potential as well as refractory period. This drug is used to treat and suppress ventricular arrhythmias, particularly ventricular fibrillation and ventricular tachycardia. ( NCI )]
UMLS (NCI) C0006168- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Bretylium Compounds
bretylium
bretylium
Relation/CHD: BRETYLIUM TOSYLATE 2 MG/ML
BRETYLIUM TOSYLATE 4 MG/ML
BRETYLIUM TOSYLATE 100 MG/ML
BRETYLIUM TOSYLATE 50 MG/ML
BRETYLIUM TOSYLATE 4 MG/ML
BRETYLIUM TOSYLATE 100 MG/ML
BRETYLIUM TOSYLATE 50 MG/ML
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