2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-Ethyl-5-(1-methylbutyl), Monosodium Salt

[The sodium salt of pentobarbital, a short-acting barbituric acid derivative with central nervous system (CNS) depressant property. Pentobarbital sodium binds to the gamma-aminobutyric acid (GABA)-A subtype receptor, resulting in modulation of chloride transport through receptor channels and potentiation of GABA-induced increases in chloride conductance. This enhances postsynaptic responses to the inhibitory actions of GABA and causes CNS depression. In addition, this agent inhibits glutamate induced nerve depolarization and depresses voltage-activated calcium currents. ( NCI )]

UMLS (NCI) C0700349

Organic Chemical
Pharmacologic Substance

Relation/PAR: PENTOBARBITAL

Relation/CHD: PENTOBARBITAL NA PWDR
PENTOBARBITAL SODIUM 60 MG
PENTOBARBITAL SODIUM 50 MG
PENTOBARBITAL SODIUM 50 MG/ML
PENTOBARBITAL SODIUM 30 MG
PENTOBARBITAL SODIUM 120 MG
PENTOBARBITAL SODIUM 100 MG
PENTOBARBITAL SODIUM 200 MG
PENTOBARBITAL SODIUM 20 MG/5ML

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