A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
Adenovirus E1b19k-Binding Protein B5
[BCL2/Adenovirus E1B 19kd Interacting Protein 3-Like, encoded by the BNIP3L gene, is a member of the BCL2/adenovirus E1B 19 kD-interacting protein (BNIP) family. It promotes apoptosis by interacting with the antiapoptotic E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as cellular antiapoptotic proteins Bcl2 and Bcl2L1. It can overcome the suppressor bcl-2 and bcl-xl, although high levels of bcl-xl expression will inhibit apoptosis. This protein is a functional homolog of BNIP3, a proapoptotic protein, and may function simultaneously with BNIP3. It may play a role in tumor suppression. (From LocusLink) ( NCI )]
UMLS (NCI) C0662972- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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