A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
Adult T Cell Leukemia-Derived PMA-Responsive Protein
[Expressed by PMA-induced, p53-responsive immediate-early-response gene human PMAIP1 Gene, 54-aa Immediate-Early-Response Protein APR contains a BH3 motif and can induce apoptosis in various cells in a BH3-dependent manner. PMAIP1 shows highest similarity to p53- and X-ray responsive 103-aa Noxa protein (mouse) with 2 BH3 motifs. Noxa exhibits BH3-dependent localization to mitochondria and interacts with antiapoptotic BCL2 family proteins, resulting in activation of caspase-9. PMAIP1/Noxa may mediate p53-dependent apoptosis in cells exposed to noxious stresses. (NCI) ( NCI )]
UMLS (NCI) C1334155ATL-Derived PMA-Responsive Protein
Immediate-Early-Response Protein APR
NOXA
Phorbol-12-Myristate-13-Acetate-Induced Protein 1
PMA-Induced Protein 1
PMAIP1
Immediate-Early-Response Protein APR
NOXA
Phorbol-12-Myristate-13-Acetate-Induced Protein 1
PMA-Induced Protein 1
PMAIP1
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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