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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
B B B0 B1 B4 B7 B8 BA BB BC BD BE BF BG BH BI BK BL BM BN BO BP BR BS BT BU BV BW BX BY BZ
BR BRA BRC BRD BRE BRF BRI BRK BRM BRO BRP BRR BRS BRT BRU BRW BRY

Breast Cancer Estrogen-Inducible Protein

[Expressed in breast, pancreas, stomach, and gastrointestinal epithelium, estrogen-responsive human TFF1 Gene (Trefoil Family) encodes cysteine-rich secretory 84-aa 9-kD (precursor) PS2 Protein, a likely tumor suppressor containing one P-type trefoil domain and a 40-aa domain with three conserved disulfides. TFF1 appears to play a complex repressor role in cell progression towards S phase (G1/S transition) and in apoptosis; TFF1 may promote cell differentiation and tissue repair. TFF1 may protect the gastrointestinal mucosa from insults, stabilize the mucus layer, and affect epithelial healing; strong expression is found in GI tract regenerative tissues. The exact function of TFF1/PS2 has not yet been determined. (NCI) ( NCI )]
UMLS (NCI) C0072523
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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