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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
B B B0 B1 B4 B7 B8 BA BB BC BD BE BF BG BH BI BK BL BM BN BO BP BR BS BT BU BV BW BX BY BZ
BR BRA BRC BRD BRE BRF BRI BRK BRM BRO BRP BRR BRS BRT BRU BRW BRY

Breast Epithelial Antigen BA46

[Expressed in mammary epithelia and activated macrophages by human MFGE8 Gene, 387-aa 43-kDa (precursor) Milk Fat Globule-EGF Factor 8 Protein is a multidomain cell surface (and secreted) protein that contains an EGF-like domain, C-terminal F5/8 type C domains, and the cell adhesion tripeptide RGD. MFGE8 recognizes aminophospholipids (phosphatidylserine) and binds to cells via its RGD motif; MFGE8 binds strongly to cells expressing alpha-V-beta-3 integrin. Expressed by activated macrophages, MFGE8 specifically binds to apoptotic cells and appears to promote macrophage phagocytosis of apoptotic cells. MFGE8 is overexpressed in several carcinomas. (NCI) ( NCI )]
UMLS (NCI) C0388561
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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