UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
C C- C1 C3 C5 C6 C7 CA CB CC CD CE CF CG CH CI CJ CK CL CM CN CO CP CQ CR CS CT CU CV CW CX CY CZ
CH CH1 CHA CHC CHD CHE CHG CHH CHI CHK CHL CHN CHO CHP CHR CHS CHU CHV CHY

CHK

[Expressed in various myeloid cells, brain, and lung by human MATK Gene (CSK Family), 507-aa 56-kDa cytoplasmic Megakaryocyte-Associated Tyrosine Kinase is similar to CSK tyrosine kinase. MATK contains an SH2 and SH3 domain, a catalytic domain, and a unique N-terminus; it lacks myristylation signals, a negative regulatory phosphorylation site, and an autophosphorylation site. Able to phosphorylate and inactivate SRC tyrosine kinases, MATK may regulate SRC activity in brain by phosphorylating the C-terminal negative regulatory tyrosine. Likely to play a significant role in signal transduction in hematopoietic cells, MATK may inhibit T-cell proliferation. (NCI) ( NCI )]
UMLS (NCI) C0250935
 
Amino Acid, Peptide, or Protein
Enzyme

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