Cyclohexanecarboxylic Acid, 4-(aminomethyl)-, trans-
[A synthetic derivative of the amino acid lysine with antifibrinolytic activity. With strong affinity for the five lysine-binding sites of plasminogen, tranexamic acid competitively inhibits the activation of plasminogen to plasmin, resulting in inhibition of fibrinolysis; at higher concentrations, this agent noncompetitively inhibits plasmin. This agent has a longer half-life, is approximately ten times more potent, and is less toxic than aminocaproic acid, which possesses similar mechanisms of action. ( NCI )]
UMLS (NCI) C0040613- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Cyclohexanecarboxylic Acids
[BL300] ANTIHEMORRHAGICS
[BL300] ANTIHEMORRHAGICS
Relation/CHD: TRANEXAMIC ACID PWDR
TRANEXAMIC ACID 100 MG/ML
TRANEXAMIC ACID 500 MG
TRANEXAMIC ACID 100 MG/ML
TRANEXAMIC ACID 500 MG
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