[A recombinant, chimeric cytokine that exerts a variety of effects on the hematopoietic and immune systems. Progenipoietin consists of portions of granulocyte colony-stimulating factor (G-CSF) and the ligand for human fetal liver tyrosine kinase-3 (FLT3). When administered in vivo, both molecules have been shown to augment the number of circulating dendritic cell (DC) precursors. This agent also appears to be anti-apoptotic for some cell types. (NCI04) ( NCI )]
UMLS (NCI) C0879506Flt-3 ligand/G-CSF fusion protein
Progenipoetin
Progenipoietin
ProGP
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance