Formamide, N-methyl
[A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. (NCI04) ( NCI )]
UMLS (NCI) C0066373- Organic Chemical
- Pharmacologic Substance
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