[The decanoate ester of haloperidol, a phenylbutylpiperadine derivative with antipsychotic, neuroleptic and antiemetic effects. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain leading to antidelusionary and antihallucinagenic effects. The antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) account for its antiemetic activity. ( NCI )]
UMLS (NCI) C0062103 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
Relation/CHD: HALOPERIDOL DECANOATE 50 MG/ML
HALOPERIDOL DECANOATE 100 MG/ML