[In more than 95% of cases, a monoclonal B-cell lymphoproliferation characterized by a bimodal age distribution (15-30 years of life and late life), often associated with EBV infection. In less than 5% of cases, this is a monoclonal proliferation of T-lymphocytes. Morphologically, it is characterized by the presense of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases. — 2004 ( NCI )]
UMLS (NCI) C1333064Classical Hodgkin Lymphoma
Classical Hodgkin's Lymphoma