cPLA2 Interacting Protein
[TIP60 interacts with the activation domain of Tat, an activator of HIV gene expression. The yeast SAS2 transcriptional silencing protein, important for exit from the cell cycle, is closely related to TIP60. The widely expressed cell surface amyloid-beta precursor protein is cleaved by gamma-secretase and its cytoplasmic tail forms a multimeric complex with the nuclear adaptor protein FE65 and the histone acetyltransferase TIP60. This complex potently stimulates transcription. (from OMIM 601409 and NCI) ( NCI )]
UMLS (NCI) C1336632HIV-1 Tat Interactive Protein, 60kDa
HTATIP
TAT Interacting Protein 60
TIP60
HTATIP
TAT Interacting Protein 60
TIP60
- Amino Acid, Peptide, or Protein
- Enzyme
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