- 1. CI-1033
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called tyrosine kinase inhibitors. ( NCI )] (UMLS (NCI) C0964184) =Organic Chemical; Pharmacologic Substance ;
| - 7. CI-921
- [A synthetic derivative of acridine carboxamide with antineoplastic properties. CI-921, a lipophilic and water-soluble analog of amsacrine, inhibits the enzyme topoisomerase ll, thereby blocking DNA replication and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0055687) =Organic Chemical; Pharmacologic Substance ;
|
- 2. CI-1040
- [An agent that inhibits both mitogen-activated protein kinase kinases 1 and 2 (MEK1 and MEK2), substrates of Raf and phosphorylates extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), preventing phosphorylation and activation of the Mitogen-Activated Protein Kinase (MAPK) pathways, involved with signal transduction pathways and tumor proliferation. ( NCI )] (UMLS (NCI) C1134610) =Organic Chemical; Pharmacologic Substance ;
| - 8. CI-937
- (UMLS (NCI) C0701504) =Organic Chemical; Pharmacologic Substance
|
- 3. CI-1042
- [A modified cold virus that selectively grows in and destroys certain types of cancer cells and leaves normal cells undamaged. ( NCI )] (UMLS (NCI) C0678040) =Virus ;
| - 9. CI-941
- (UMLS (NCI) C0950689) =Organic Chemical; Pharmacologic Substance
|
- 4. CI-825
- (UMLS (NCI) C0733529) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 10. CI-942
- (UMLS (NCI) C0701493) =Organic Chemical; Pharmacologic Substance
|
- 5. CI-898
- (UMLS (NCI) C0701241) =Organic Chemical; Pharmacologic Substance
| - 11. CI-981
- (UMLS (NCI) C0082029) =Organic Chemical; Pharmacologic Substance ;
|
- 6. CI-904
- (UMLS (NCI) C0109747) =Organic Chemical; Pharmacologic Substance ;
| - 12. CI-994
- (UMLS (NCI) C0217595) =Organic Chemical; Pharmacologic Substance ;
|
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