- 601. 1-Hexadecanaminium, N-(2-(((4-methoxyphenyl)methyl)-2-pyrimidinylamino)ethyl)-N,N-dimethyl-, Bromide
- [A cationic surface-active compound. As an additive to pharmacologic formulations, thonzonium bromide causes dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. ( NCI )] (UMLS (NCI) C0724705) Ammonium, hexadecyl(2-((p-methoxybenzyl)-2-pyrimidinylamino)ethyl)dimethyl-, Bromide(8CI);
Thonzonium Bromide;
THONZONIUM BROMIDE PREPARATION =Organic Chemical; Pharmacologic Substance ;
=THONZONIUM;
=THONZONIUM BROMIDE 0.5 MG/ML | - 651. 10
- [Maxillary left lateral incisor ( HL7V3.0 )] (UMLS (HL7) C0227045) tooth 10 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 602. 1-Hexadecanol
- [A synthetic, solid, fatty alcohol and nonionic surfactant. Cetyl alcohol is used as an emulsifying agent in pharmaceutical preparations. ( NCI )] (UMLS (NCI) C0055152) =Organic Chemical; Pharmacologic Substance ;
=Fatty Alcohols;
Inactive Ingredient Preparations =AQUA-A CREAM;
AQUADERM CREAM;
AQUADERM LOTION;
MOISTUREL CREAM,TOP;
MOISTUREL LOTION;
UREA 25% LOTION;
CETAPHIL CREAM;
CETAPHIL LOTION;
SALICYLIC ACID 10% CREAM (GRAMS);
COLLOIDAL OATMEAL 1% LOTION (ML);
ALUMINUM ACETATE 1%/CAMPHOR 3%/MENTHOL 0.5%/PHENOL 1% CREAM,TOP;
BENZOIC ACID 12%/SALICYLIC ACID 6% CREAM,TOP;
CETYL ALCOHOL LIQUID;
EXTRA STRENGTH HAND & NAIL LOTION;
GLYCERIN/PETROLATUM/ZINC OXIDE LOTION;
I.S.P. LOTION;
LOBANA BODY LOTION;
MOISTURE DERM LOTION;
MOISTURIZING LOTION;
MONOBASE CREAM,TOP;
NUSOAP CLEANSING LIQUID;
NUSOAP SOAP;
OCTYL METHOXYCINNAMATE/OCTYL SALICYLATE/OXYBENZONE SPF-15 LOTION;
OXICONAZOLE 1% LOTION;
OXYBENZONE 2%/PADIMATE O 5% LOTION;
OXYBENZONE 3%/PADIMATE O 8% LOTION;
OXYBENZONE/PADIMATE O LOTION;
RAYNOX CREAM;
SPECTRO-JEL TOP;
SULFUR 5%/SULFURATED POTASH/ZINC OXIDE 10% CREAM,TOP;
THERI-CARE LOTION;
UNDECYLENIC ACID 5%/ZINC UNDECYLENATE 20% CREAM,TOP;
VASELINE INTENSIVE CARE LOTION;
terbinafine 10 MG/ML Topical Cream;
KERI FACIAL CLEANSER LIQUID,TOP;
POVIDONE IODINE 5% CREAM,TOP;
CETYL ALCOHOL/COLFOSCERIL PALMITATE/TYLOXAPOL SUSP,ITRC;
CETYL ALCOHOL 1 % | - 652. 10 day report
- (UMLS (HL7) C1546917) =Temporal Concept =Report timing;
|
- 603. 1-Methoxy-2-nitrobenzene
- [A synthetic, colorless or slightly yellow liquid that is insoluble in water and soluble in most organic solvents. It is used primarily as a precursor to o-anisidine, which is used extensively in the synthesis of azo dyes. 2-Nitroanisole is also used as an intermediate for the preparation of pharmaceuticals products. The primary routes of potential human exposure to 2-nitroanisole are dermal contact, ingestion and inhalation. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0046435) =Organic Chemical; Hazardous or Poisonous Substance
| - 653. 10 days
- (UMLS (HL7) C1547061) =Temporal Concept =Time delay post challenge;
|
- 604. 1-Methyl-1-nitrosourea
- [methylated nitrosourea compound with alkylating, carcinogenic, and mutagenic properties. ( CSP )] (UMLS (NCI) C0025803) =Organic Chemical; Hazardous or Poisonous Substance ;
=Cancer Causing Agents;
nitrosourea | - 654. 10 minutes post challenge
- (UMLS (HL7) C1547062) =Temporal Concept =Time delay post challenge;
|
- 605. 1-Methyl-3-nitro-1-nitrosoguanidine
- [radiomimetic, DNA strand breaking agent used as a "direct acting" experimental carcinogen. ( CSP )] (UMLS (NCI) C0025800) =Organic Chemical; Hazardous or Poisonous Substance ;
=antimetabolite;
Cancer Causing Agents;
nitrosoguanidine;
| - 655. 10,11-Benzofluoranthene
- [A yellowish, aromatic hydrocarbon consisting of five fused rings and formed by the incomplete combustion of organic matter. Benzo(j)fluoranthene is primarily found in certain foods, cigarette smoke, gasoline exhaust, coal tar, coal smoke, oil heat emissions, crude oils and used motor oils. This substance is used only for research purposes. Benzo(j)fluoranthene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0053206) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
|
- 606. 1-methylethyl-2-chloro-5-[[5,6-dihydro-2-methyl- 1, 4-oxathiin-3-yl-carbonyl]-amino]benzoate
- (UMLS (NCI) C0220323) =Organic Chemical; Pharmacologic Substance
| - 656. 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
- [A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses. ( NCI )] (UMLS (NCI) C0069751) =Organic Chemical; Pharmacologic Substance =[CN400] ANTICONVULSANTS;
5H-Dibenz(b,f)azepine-5-carboxamide =OXCARBAZEPINE 300 MG;
OXCARBAZEPINE 600 MG;
OXCARBAZEPINE 150 MG;
OXCARBAZEPINE 300 MG/5ML |
- 607. 1-Naphthacenecarboxylic acid, 4-[[O-2,6-dideoxy-.alpha.-L-lyxo-hexopyranosyl-(1.fwdarw.4)-O-2, 6-dideoxy-.alpha.-L-lyxo-hexopyranosyl-(1.fwdarw.4)-2,3, 6-trideoxy-3-(dimethylamino)-.alpha.-L-lyxo-hexopyranosyl]oxy]-2-e thyl-1,2,3,4,6,11-hexahydro-2,5,7,10
- [An antineoplastic oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Actinosporangium bohemicum. Marcellomycin intercalates into DNA and induces DNA crosslinks, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also induces differentiation in HL-60 promyelocytic leukemia cells by interfering with glycoprotein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0065718) =Organic Chemical; Antibiotic
| - 657. 10,11delta-Amitriptyline Hydrochloride
- [A centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity. The exact mechanism of action of cyclobenzaprine hydrochloride has not been fully determined. However, it primarily acts at the brain stem to reduce tonic somatic motor activity, influencing both gamma and alpha motor neurons. This leads to a reduction in muscle spasms. ( NCI )] (UMLS (NCI) C0125988) =Organic Chemical; Pharmacologic Substance ;
=CYCLOBENZAPRINE;
=CYCLOBENZAPRINE HYDROCHLORIDE 10 MG |
- 608. 1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride
- [An oral calcimimetic. Cinacalcet hydrochloride increases the sensitivity of the calcium-sensing receptors on the chief cells in the parathyroid gland to extracellular calcium, thereby reducing parathyroid hormone secretion. A reduction in parathyroid hormone levels inhibits osteoclast activity, favourably impacts bone-specific alkaline phosphatase, bone turnover, and bone fibrosis, and leads to normalization of serum calcium and phosphate levels. Cinacalcet hydrochloride is a treatment option for primary and secondary hyperparathyroidism and parathyroid carcinoma. ( NCI )] (UMLS (NCI) C1260199) CINACALCET HCL UNIDENTIFIED;
CINACALCET HCL UNIDENTIFIED;
CINACALCET HYDROCHLORIDE;
=Organic Chemical; Pharmacologic Substance ;
| - 658. 10-((3-Chloro-4-methoxyphenyl)methyl)-6-methyl-3-(2-methylpropyl)-16-(1-(3-phenyloxiranyl)ethyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
- [The cryptophycins are a family of 16-membered macrolide antimitotic agents isolated from the cyanobacteria Nostoc sp. The mechanism of anticancer activity of the cryptophycins has been associated with their destabilization of microtubules and induction of bcl-2 phosphorylation leading to apoptosis. Cryptophycins demonstrated activity against the wide spectrum of solid tumors including those that overexpress the multidrug resistance efflux pump P-glycoprotein. (NCI) ( NCI )] (UMLS (NCI) C0257217) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 609. 1-NBaP
- [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 1-nitrobenzo(a)pyrene consists of five fused rings with a nitro-group attached to the first carbon atom of the aromatic hydrocarbon ring in with potential carcinogenicity. ( NCI )] (UMLS (NCI) C0044504) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 659. 10-(2-Propynyl)estr-4-ene-3,17-dione
- (UMLS (NCI) C0044695) =Steroid; Pharmacologic Substance ;
|
- 610. 1-Nitrobenzo[a]pyrene trans-7,8-Dihydrodiol
- (UMLS (NCI) C0768962) =Organic Chemical
| - 660. 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine
- [A phenothiazine derivative and a dopamine antagonist with antipsychotic and antiemetic activities. Trifluoperazine exerts its antipsychotic effect by blocking central dopamine receptors, thereby preventing effects such as delusions and hallucinations caused by an excess of dopamine. This agent also functions as a calmodulin inhibitor, thereby leading to elevation of cytosolic calcium. ( NCI )] (UMLS (NCI) C0040979) =Organic Chemical; Pharmacologic Substance ;
=Phenothiazine;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS =10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine Dihydrochloride |
- 611. 1-Nitropyrene
- [A synthetic, light sensitive, yellow crystalline solid that is practically insoluble in water and soluble in diethyl ether, acetone, ethanol, benzene and toluene. It is not used for any commercial applications and is used only for research purposes, principally as a marker for exposure to nitro-polycyclic aromatic hydrocarbons from diesel exhaust. When heated to decomposition, 1-nitropyrene emits toxic fumes of nitrogen oxides. This compound is found in particulate emissions from combustion products, of which diesel exhaust is the principle source. The primary route of potential human exposure to 1-nitropyrene is inhalation. This compound is one of the most abundant mononitroarenes detected in ambient air. Occupational exposure to 1-nitropyrene occurs primarily in workers exposed to diesel engine exhaust in the transport industry. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0044508) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 661. 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine Dihydrochloride
- [A hydrochloride salt form of trifluoperazine, a phenothiazine derivative and a dopamine antagonist with antipsychotic and antiemetic activities. Trifluoperazine exerts its antipsychotic effect by blocking central dopamine receptors, thereby preventing effects such as delusions and hallucinations caused by an excess of dopamine. This agent also functions as a calmodulin inhibitor, thereby leading to elevation of cytosolic calcium. ( NCI )] (UMLS (NCI) C0304381) =Organic Chemical; Pharmacologic Substance =10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine;
=TRIFLUOPERAZINE HYDROCHLORIDE 2 MG/ML;
TRIFLUOPERAZINE HYDROCHLORIDE 1 MG;
TRIFLUOPERAZINE HYDROCHLORIDE 2 MG;
TRIFLUOPERAZINE HYDROCHLORIDE 5 MG;
TRIFLUOPERAZINE HYDROCHLORIDE 10 MG/ML;
TRIFLUOPERAZINE HYDROCHLORIDE 10 MG;
|
- 612. 1-Nitrosopiperidine
- [A clear, yellow, oily, liquid that is light sensitive and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosopiperidine is used in laboratory research to induce tumors in experimental animals. This substance is naturally formed in foods that contain sodium nitrite as a preservative, including meat, fish and cheese, as a result of nitrosation of piperidine in the presence of nitrite. N-Nitrosopiperidine is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068235) =Organic Chemical; Hazardous or Poisonous Substance
| - 662. 10-(3-(Dimethylamino)propyl)phenothiazine Monohydrochloride
- [The hydrochloride salt form of promazine, a phenothiazine derivative with antipsychotic and antiemetic properties. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks alpha-adrenergic receptors and exhibits strong anticholinergic activity. ( NCI )] (UMLS (NCI) C0546875) =Organic Chemical; Pharmacologic Substance =PROMAZINE;
=PROMAZINE HYDROCHLORIDE 50 MG/ML;
|
- 613. 1-Nitrosopyrrolidine
- [A clear, yellow, oily, liquid nitrosamine that decomposes when exposed to light and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosopyrrolidine is used in laboratory research to induce tumors in experimental animals. This substance may be formed during cooking of foods that contain sodium nitrite as a preservative, including meat, fish and cheese. Exposure to N- Nitrosopyrrolidine irritates the skin and eyes and can damage the liver and kidneys. This substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0027253) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 663. 10-19% BDY BRN/10-19% 3D
- [ ] (UMLS (ICD9CM) C0161331) =Injury or Poisoning
|
- 614. 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine
- [produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells; several molecular species of platelet activating factor have been identified which vary in the length of the O-alkyl side chain; an important mediator of bronchoconstriction. ( CSP )] (UMLS (NCI) C0032172) =Lipid; Immunologic Factor =Blood Coagulation Factor;
| - 664. 10-19% BDY BRN/3 DEG NOS
- [ ] (UMLS (ICD9CM) C0161330) =Injury or Poisoning
|
- 615. 1-Octadecyl-2-methoxy-rac-glycero-3-phosphocholine
- [A synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for edelfosine has not been fully elucidated. Targeting cellular membranes, edelfosine modulates membrane permeability, membrane lipid composition, and phospholipid metabolism. Edelfosine also inhibits the phosphatidylinositol 3 kinase (PI3K)-AKT/PKB survival pathway, possibly activating the pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. In addition, this agent inhibits protein kinase C, intracellular activation of the Fas/CD95 receptor, and intracellular acidification. Anti-leishmanial activity may be due to inhibition of a glycosomal alkyl-specific-acylCoA acyltransferase. (NCI) ( NCI )] (UMLS (NCI) C0044549) =Lipid; Pharmacologic Substance ;
| - 665. 10-chloro-4-hydroxy-6-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-2,8,10,12-tetraen-5-one
- [A benzodiazepine derivative with antidepressant, sedative, hypnotic and anticonvulsant properties. Temazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreases neuronal excitability. ( NCI )] (UMLS (NCI) C0039468) =Organic Chemical; Pharmacologic Substance =Benzodiazepinones;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS =TEMAZEPAM 15 MG;
TEMAZEPAM 30 MG;
TEMAZEPAM 7.5 MG;
|
- 616. 1-p-beta-dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
- [selective estrogen receptor modulator; it is agonist for bone tissue and cholesterol metabolism but antagonist in mammary and uterine tissues. ( CSP )] (UMLS (NCI) C0039286) =Organic Chemical; Pharmacologic Substance ;
=amine;
Antiestrogen;
stilbene;
selective estrogen receptor modulator;
[AN500] ANTINEOPLASTIC HORMONES;
=(Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine;
(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate;
[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone;
(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate | - 666. 10-Deacetyltaxol
- [An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. ( NCI )] (UMLS (NCI) C0044663) =Organic Chemical
|
- 617. 1-p-carboxy-3,3-dimethylphenyltriazine
- (UMLS (NCI) C0088835) =Organic Chemical; Pharmacologic Substance
| - 667. 10-EdAM
- [An anticancer drug that belongs to a family of drugs called antimetabolites. ( NCI )] (UMLS (NCI) C0044667) =Organic Chemical; Pharmacologic Substance ;
|
- 618. 1-phenyl-2-diethyl-amino-1-propanone Hydrochloride
- [A sympathomimetic amine structurally similar to amphetamine with anorexiant activity. Diethylpropion hydrochloride stimulates the central nervous system and increases the release of norepinephrine and dopamine from nerve terminals and inhibits their uptake. This suppresses appetite, increases motor activity, causes euphoria, mental alertness and excitement. This drug may also cause an increase in heart rate and blood pressure. Diethylpropion hydrochloride is used in the treatment of obesity. ( NCI )] (UMLS (NCI) C0282133) =Organic Chemical; Pharmacologic Substance ;
=DIETHYLPROPION;
=DIETHYLPROPION HYDROCHLORIDE 75 MG;
DIETHYLPROPION HYDROCHLORIDE 25 MG | - 668. 10-O-Elsaminosylelsarosylchartarin
- [An heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication. (NCI04) ( NCI )] (UMLS (NCI) C0059041) =Organic Chemical; Antibiotic ;
|
- 619. 1-Phenyl-Methyl-2-Piperazinyl-1H-Benzimidazole Hydrochloride
- [A drug that prevents or reduces nausea and vomiting. ( NCI )] (UMLS (NCI) C0758799) Lerisetron =Organic Chemical; Pharmacologic Substance ;
| - 669. 10-Propargyl-10-Deazaaminopterin
- [A substance that is being studied as an anticancer drug. It belongs to the family of drugs called folate analogues. ( NCI )] (UMLS (NCI) C0879404) PDX =Organic Chemical; Pharmacologic Substance ;
|
- 620. 1-Phosphatidylinositol 3-Kinase
- [An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. (from LocusLink) ( NCI )] (UMLS (NCI) C0044602) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;
| - 670. 10-[(1-Methyl-3-pyrrolidinyl)methyl]-10H-phenothiazine Hydrochloride
- (UMLS (NCI) C0304371) =Organic Chemical; Pharmacologic Substance =METHDILAZINE;
|
- 621. 1-Phosphatidylinositol 3-Kinase
- [Phosphoinositide-3-Kinase, Catalytic, Gamma Polypeptide, encoded by the PIK3CG gene, belongs to the PI3/PI4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. (from LocusLink) ( NCI )] (UMLS (NCI) C0285761) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 671. 100+ years old
- [elderly or aged humans of the age 100 or above; also index with appropriate human and clinical research terms. ( CSP )] (UMLS (CSP) C0007667) =Age Group =85+ years old;
|
- 622. 1-Phosphatidylinositol Phosphodiesterase
- [Encoded by human PLCG2 Gene, 1265-aa 148-kDa Phospholipase C Gamma 2 is a crucial enzyme that generates DAG and IP3 second messengers in the transmembrane signaling of ligand-activated growth factor receptors. Containing a PI-PLC X-box catalytic domain, a PI-PLC Y-box catalytic domain, a C2 domain, a PH domain, 2 SH2 domains, and an SH3 domain, PLCG2 phospholipase activity increases upon phosphorylation on tyrosine residues following activation of growth factor and immune system receptors. (NCI) ( NCI )] (UMLS (NCI) C1377870) 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Gamma 2;
EC 3.1.4.11;
Phosphatidylinositol-Specific Phospholipase C-Gamma;
Phosphoinositide Phospholipase C;
Phospholipase C Gamma 2;
Phospholipase C, Gamma 2 (Phosphatidylyinositol-specific);
Phospholipase C-Gamma-2;
PI-Specific PLC Gamma;
PLCG2;
PLC-Gamma-2;
PLC-IV =Amino Acid, Peptide, or Protein; Enzyme | - 672. 10a
- [Maxillary left lateral incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553642) =Medical Device =Artificial dentition;
|
- 623. 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 3
- [Expressed in many tissues by human PLCB3 Gene, 1234-aa 139-kDa membrane-bound Phospholipase C Beta 3 contains a catalytic PI-PLC X-box domain, a catalytic PI-PLC Y-box domain, and a C2 domain. Activated in response to stimulation by hormones, growth factors, neurotransmitters, and other ligands, PLCB3 is a key enzyme in initiating receptor-mediated signal transduction by mediating production of DAG and IP3 second messengers. (NCI) ( NCI )] (UMLS (NCI) C1377871) Phosphoinositide Phospholipase C;
Phospholipase C Beta 3;
Phospholipase C Beta 3, Phosphatidylinositol-Specific;
PLCB3;
PLC-Beta-3 =Amino Acid, Peptide, or Protein; Enzyme | - 673. 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-,(E)-2-butenedioate(1:1)
- [The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils. ( NCI )] (UMLS (NCI) C0043443) =Organic Chemical; Pharmacologic Substance ;
=KETOTIFEN;
=KETOTIFEN FUMARATE 0.025 % |
- 624. 1-Phosphatidylinositol-4-Phosphate 5-Kinase
- [Expressed ubiquitously (high in brain) by human PIP5K2A Gene (PtdIns(4)P-5-Kinase Family), 406-aa 46-kDa Phosphatidylinositol-4-Phosphate 5-Kinase Type II Alpha is a likely homodimer that catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-biphosphate, the precursor to second messengers of phosphoinositide signal transduction pathways involved in regulation of secretion, cell proliferation, differentiation, and motility. PIP5K2A does not show homology to other kinases, but the protein does exhibit kinase activity. (NCI) ( NCI )] (UMLS (NCI) C1368110) 1-Phosphatidylinositol-4-Phosphate Kinase;
Diphosphoinositide Kinase;
Phosphatidylinositol-4-Phosphate 5-Kinase Type II Alpha;
PIP5K2A;
PIP5KII-Alpha;
PIPK;
PtdIns(4)P-5-Kinase;
Type II Phosphatidylinositol-4-Phosphate 5-Kinase 53 K;
=Amino Acid, Peptide, or Protein; Enzyme | - 674. 10i
- [Maxillary left lateral incisor implant ( HL7V3.0 )] (UMLS (HL7) C1552174) =Medical Device =Artificial dentition;
|
- 625. 1-Phosphatidylinositol-4-Phosphate Kinase
- [Abundantly expressed (6.3-kb mRNA) in many tissues, human PIP5K2B Gene (PtdIns(4)P-5-Kinase Family) encodes 416-aa plasma membrane targeted Phosphatidylinositol-4-Phosphate 5-Kinase Type II Beta, a homodimer 78% identical in sequence to PIP5K2A that catalyzes phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate, precursor to second messengers of phosphoinositide signal transduction pathways involved in regulation of secretion, cell proliferation, differentiation, and motility. PIP5K isoforms possess almost no homology to kinase motifs in other phosphatidylinositol, protein, and lipid kinases. Conserved basic residues may form a dual specificity site for phosphatidylinositol 3- and 5-phosphates. PIP5K2B specifically interacts with the juxtamembrane region of TNFR1; PIP5K2B activity is increased by TNF-alpha. (NCI) ( NCI )] (UMLS (NCI) C1368108) Diphosphoinositide Kinase;
Phosphatidylinositol-4-Phosphate 5-Kinase Type II Beta;
PIP5KIIB;
PIPKII-Beta;
PTDINS(4)P-5-Kinase;
=Amino Acid, Peptide, or Protein; Enzyme | - 675. 10p
- [Maxillary left lateral incisor prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553565) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 626. 1-Piperazinecarboxamide, 4-(6-Methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-
- [A piperazinyl quinazoline receptor tyrosine kinase inhibitor with antineoplastic activity. Tandutinib inhibits the autophosphorylation of FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGF (platelet-derived growth factor) receptor tyrosine kinases, thereby inhibiting cellular proliferation and inducing apoptosis. ( NCI )] (UMLS (NCI) C1143028) Tandutinib;
=Organic Chemical; Pharmacologic Substance ;
| - 676. 10pd
- [Maxillary left lateral incisor distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553566) =Medical Device =Artificial dentition;
|
- 627. 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-(9CI)
- [2-trifluoromethyl derivative of perphenazine, used in treatment of psychoses. ( CSP )] (UMLS (NCI) C0016368) =Organic Chemical; Pharmacologic Substance ;
=Phenothiazine;
[CN700] ANTIPSYCHOTICS;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS;
=Flufenazine Decanoate;
Fluphenazine Enanthate;
FLUPHENAZINE HYDROCHLORIDE;
Flufenazine Decanoate;
Fluphenazine Enanthate;
FLUPHENAZINE HYDROCHLORIDE | - 677. 10pm
- [Maxillary left lateral incisor mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553564) =Medical Device =Artificial dentition;
|
- 628. 1-Piperidinepropanoic Acid, 4-(methoxycarbonyl)-4-((1-oxopropyl)phenylamino)-, Methyl Ester, Monohydrochloride
- [The hydrochloride salt form of remifentanil, a synthetic anilidopiperidine derivative and short-acting opiate agonist with analgesic and anesthetic properties. Remifentanil selectively binds to and activates the mu-opioid receptor, thereby producing analgesia, respiratory depression, miosis, reduced gastrointestinal motility, and euphoria. ( NCI )] (UMLS (NCI) C0771827) Remifentanil Hydrochloride;
REMIFENTANIL HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance ;
=REMIFENTANIL;
=REMIFENTANIL HYDROCHLORIDE 1 MG;
REMIFENTANIL HYDROCHLORIDE 5 MG;
REMIFENTANIL HYDROCHLORIDE 2 MG | - 678. 10s
- [Supernumerary maxillary left lateral incisor ( HL7V3.0 )] (UMLS (HL7) C1552124) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
- 629. 1-Piperidinepropanol, alpha-cyclohexyl-alpha-phenyl-, Hydrochloride
- [The hydrochloride salt form of trihexyphenidyl, a synthetic, substituted piperidine with parasympatholytic activity used mostly in Parkinson's disease. Trihexyphenidyl hydrochloride antagonizes activities of acetylcholine via muscarinic receptors. This balances the cholinergic and dopaminergic activity in the basal ganglia leading to an improvement of classic Parkinson symptoms such as rigidity and tremor. In addition, triphexyphenidyl hydrochloride exerts a direct antispasmodic effect on smooth muscle. ( NCI )] (UMLS (NCI) C0003830) =Organic Chemical; Pharmacologic Substance
| - 679. 10% Formalin
- (UMLS (HL7) C1550067) =Organic Chemical; Biomedical or Dental Material ;
=Additive/Preservative;
|
- 630. 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, Chloride
- [The chloride salt form of methacholine, a direct-acting cholinergic muscarinic agonist with bronchoconstrictive, miotic, vasodilator, and cardiac vagomimetic activity. Methacholine chloride acts directly on the muscarinic receptors in the heart, eye, and lung, thereby producing parasympathomimetic effects. ( NCI )] (UMLS (NCI) C0079829) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid =Methacholine Compounds;
METHACHOLINE =METHACHOLINE CHLORIDE 100 MG;
METHACHOLINE CHLORIDE 20 MG/ML;
METHACHOLINE CHLORIDE 0.25 %;
| - 680. 10% Formalin
- [A 10% v/v solution in water of formalin( a 37% solution of formaldehyde and water). Used for tissue preservation. ( HL7V3.0 )] (UMLS (HL7) C1561470) =Intellectual Product =MaterialEntityAdditive;
|
- 631. 1-Propanol, 3,3'-, dimethanesulfonate (ester), hydrochloride
- (UMLS (NCI) C0971903) 1-Propanol, 3,3'-Iminobis-, Dimethanesulfonate (Ester), Hydrochloride (9CI;
1-Propanol, 3,3'-iminobis-, dimethanesulfonate (ester), hydrochloride (9CI);
1-Propanol, 3,3'-iminodi-, dimethanesulfonate (ester), hydrochloride (8CI);
1-Propanol-3,3'-iminodidimethanesulfonatehydrochloride;
3, 3'-Dimesyloxydipropylamine HCl;
3, 3'-Dimesyloxydipropylamine hydrochloride;
3, 3'-Iminodi-1-propanol Di(methanesulfonate) HCl;
3, 3'-Iminodi-1-propanol di(methanesulfonate) hydrochloride;
3, 3'-Iminodi-1-propanol Dimethanesulfonate Ester HCl;
3, 3'-Iminodi-1-propanol dimethanesulfonate ester hydrochloride;
3,3'-Imidodi-1-propanol, Dimethanesulfonate (Ester) HCl;
3,3'-Imidodi-1-propanol, dimethanesulfonate (ester), hydrochloride;
Bis(3-mesyloxypropyl)amine HCl;
Bis(3-mesyloxypropyl)amine hydrochloride;
IPD hydrochloride =Organic Chemical; Pharmacologic Substance ;
| - 681. 10^3/mcl
- [A derived unit expressed as a number or quantity of objects in billions per unit of volume equal to one liter, or the equivalent in milliliters or microliters. ( NCI )] (UMLS (NCI) C0456615) =Quantitative Concept
|
- 632. 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, Hydrochloride
- [The hydrochloride salt form of propafenone with class 1C antiarrhythmic effects. Propafenone hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby reducing sodium influx required for the initiation and conduction of impulses in Purkinje and myocardial cells. This agent produces a marked depression of phase 0 and prolonged effective refractory period in the atrio-ventricular nodal and His-Purkinje tissue, resulting in a profound decrease in excitability, conduction velocity and automaticity, thereby counteracting atrial and ventricular arrythmias. ( NCI )] (UMLS (NCI) C0700465) =Organic Chemical; Pharmacologic Substance =PROPAFENONE;
=PROPAFENONE HYDROCHLORIDE 150 MG;
PROPAFENONE HYDROCHLORIDE 225 MG;
PROPAFENONE HYDROCHLORIDE 300 MG | - 682. 10^9 Cells/L
- [A unit of cell concentration expressed as a number of cells in billions in unit volume equal to one liter. ( NCI )] (UMLS (NCI) C0456524) =Quantitative Concept
|
- 633. 1-Propanone, 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-
- [A substance that is used to treat depression, and to help people quit smoking. It belongs to the family of drugs called antidepressants. ( NCI )] (UMLS (NCI) C0085208) =Organic Chemical; Pharmacologic Substance ;
=[CN600] ANTIDEPRESSANTS;
Propiophenones;
[CN609] ANTIDEPRESSANTS, OTHER;
=(+-)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone Hydrochloride;
BUPROPION 150 MG;
BUPROPION 200 MG;
BUPROPION 300 MG;
| - 683. 11
- [Maxillary left canine ( HL7V3.0 )] (UMLS (HL7) C0227046) tooth 11 =Body Part, Organ, or Organ Component =Permanent dentition;
|
- 634. 1-Propanone, 2-methyl-1,2-di-3-pyridinyl-
- [USP lists as a diagnostc aid for determination of pituitary function. ( CSP )] (UMLS (NCI) C0025876) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid =pyridine;
ACTH inhibitor;
[DX900] DIAGNOSTICS, OTHER;
=METYRAPONE 250 MG | - 684. 11,12-Benzo[k]fluoranthene
- [A pale yellow aromatic hydrocarbon consisting of five fused rings and is produced by the incomplete combustion of organic matter. Benzo(k)fluoranthene is primarily found in gasoline exhaust, cigarette smoke, coal tar, coal and oil combustion emissions, lubricating oils, used motor oils and crude oils. This substance is used only for research purposes. Benzo(k)fluoranthene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0053207) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 635. 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-
- [The hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body. ( NCI )] (UMLS (NCI) C0058831) =Organic Chemical; Pharmacologic Substance =Propiophenones;
[DE700] LOCAL ANESTHETICS, TOPICAL =1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-,hydrochloride;
| - 685. 11-beta,17-alpha,21-Trihydroxy-4-pregnene-3,20-dione 17-alpha-butyrate
- [The butyrate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2. Lack of phospholipase A2 prevents the release of arachidonic acid, precursor for inflammatory mediator prostaglandins and leukotrienes, from the cell membrane. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leading to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production. ( NCI )] (UMLS (NCI) C0352536) =Steroid; Pharmacologic Substance =(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
=HYDROCORTISONE BUTYRATE 0.1 % |
- 636. 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-,hydrochloride
- [The hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body. ( NCI )] (UMLS (NCI) C0304455) =Organic Chemical; Pharmacologic Substance =1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-;
=DYCLONINE HYDROCHLORIDE 0.5 %;
DYCLONINE HYDROCHLORIDE 1 %;
DYCLONINE HYDROCHLORIDE 01 % | - 686. 11-beta-Hydroxy-6-alpha-methylpregn-4-ene-3,20-dione
- [A topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions is accomplished. ( NCI )] (UMLS (NCI) C0065865) =Steroid; Pharmacologic Substance ;
=Pregnenediones;
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC =MEDRYSONE 1 %;
|
- 637. 1-Pyrrolidineethanamine, beta-((2-Methylpropoxy)methyl)-N-phenyl-N-(phenylmethyl)-, Monohydrochloride
- [The hydrochloride salt form of bepridil, a calcium antagonist and class IV anti-arrhythmic agent. Bepridil hydrochloride blocks calcium entry through membranous calcium channels of coronary and peripheral vascular smooth muscle, thereby dilating coronary arteries and peripheral arterioles. This increases oxygen delivery and reduces oxygen requirements. This drug is used to treat chronic stable and variant angina pectoris. ( NCI )] (UMLS (NCI) C0770909) Bepridil Hydrochloride;
BEPRIDIL HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =Bepridil;
=BEPRIDIL HYDROCHLORIDE 300 MG;
BEPRIDIL HYDROCHLORIDE 200 MG | - 687. 111 In-B3
- [A radioimmunoconjugate of monoclonal antibody (MoAb) B3 labeled with Indium 111 (In-111). MoAb B3 is a murine MoAb that recognizes a Lewis Y carbohydrate antigen present on the surface of many carcinomas. This radioimmunoconjugate emits gamma radiation and X-Ray photons that can be captured by gamma camera allowing imaging of Lewis Y expressing tissues. ( NCI )] (UMLS (NCI) C0935762) In 111 Monoclonal Antibody B3;
Indium In 111 Monoclonal Antibody B3 =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 638. 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole
- [A synthetic, imidazole derivate with broad-spectrum, antifungal activity. Clotrimazole inhibits biosynthesis of sterols, particularly ergosterol, an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in leakage and loss of essential intracellular compounds, and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0009074) =Organic Chemical; Pharmacologic Substance =imidazole;
[DE102] ANTIFUNGAL, TOPICAL;
[GU300] ANTI-INFECTIVES, VAGINAL;
[NT900] NASAL AND THROAT, TOPICAL, OTHER =CLOTRIMAZOLE 10 MG;
CLOTRIMAZOLE 100 MG;
CLOTRIMAZOLE 200 MG;
CLOTRIMAZOLE 1 % | - 688. 111 Indium
- [A radioisotope with a physical half-life of 2.83 days, used to label agents for diagnosis, disease progression and treatment. (NCI) ( NCI )] (UMLS (NCI) C0303403) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope ;
=[DX201] IMAGING AGENTS (IN VIVO) RADIOPHARMACEUTICALS;
Unclassified Ingredients =INDIUM In 111 CAPROMAB PENDETIDE |
- 639. 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
- [A synthetic piperazine with anti-emetic, sedative and histamine H1antagonistic properties. Meclizine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. Meclizine hydrochloride may exert its antiemetic effects by its anticholinergic actions or due to a direct effect on the medullary chemoreceptive trigger zone. ( NCI )] (UMLS (NCI) C0025039) =Organic Chemical; Pharmacologic Substance ;
=Benzhydryl Compounds;
Piperazines;
[CN550] ANTIVERTIGO AGENTS;
=1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine Dihydrochloride Monohydrate | - 689. 11a
- [Maxillary left canine abutment ( HL7V3.0 )] (UMLS (HL7) C1553643) =Medical Device =Artificial dentition;
|
- 640. 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine Dihydrochloride Monohydrate
- [The hydrochloride salt form of meclizine, a synthetic piperazine with anti-emetic, sedative and histamine H1 antagonistic properties. Meclizine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. Meclizine hydrochloride may exert its antiemetic effects by its anticholinergic actions or due to a direct effect on the medullary chemoreceptive trigger zone. ( NCI )] (UMLS (NCI) C0282227) =Organic Chemical; Pharmacologic Substance =1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;
=MECLIZINE HYDROCHLORIDE 15 MG;
MECLIZINE HYDROCHLORIDE 50 MG;
MECLIZINE HYDROCHLORIDE 12.5 MG;
MECLIZINE HYDROCHLORIDE 25 MG;
MECLIZINE HYDROCHLORIDE 30 MG;
| - 690. 11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-Acetate
- [The acetate salt of a synthetic glucocorticoid receptor agonist with immunosuppressive and antiinflammatory effects. Methylprednisolone acetate is converted into active prednisolone in the body, which activates glucocorticoid receptor mediated gene expression. This includes inducing synthesis of anti-inflammatory protein IkappaB-alpha and inhibiting synthesis of nuclear factor kappaB (NF-kappaB). As a result, proinflammatory cytokine production such as IL-1, IL-2 and IL-6 is down-regulated and cytotoxic T-lymphocyte activation is inhibited. Therefore, an overall reduction in chronic inflammation and autoimmune reactions may be achieved. ( NCI )] (UMLS (NCI) C0600901) =Steroid; Pharmacologic Substance ;
=(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
[RS100] ANTI-INFLAMMATORIES, RECTAL;
Unclassified Ingredients =METHYLPREDNISOLONE ACETATE 40 MG/ML;
METHYLPREDNISOLONE ACETATE 0.25 %;
METHYLPREDNISOLONE ACETATE 1 %;
METHYLPREDNISOLONE ACETATE 10 MG;
METHYLPREDNISOLONE ACETATE 20 MG/ML;
METHYLPREDNISOLONE ACETATE 80 MG/ML;
METHYLPREDNISOLONEACETATE 0.25 % |
- 641. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
- [An antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. (NCI04) ( NCI )] (UMLS (NCI) C0025942) =Organic Chemical; Pharmacologic Substance =[AM700] ANTIFUNGALS;
imidazole =1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole Mononitrate;
MICONAZOLE 10 MG/ML;
Baza Antifungal 20 MG/ML Topical Cream;
| - 691. 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-Valerate
- [The valerate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2. Lack of phospholipase A2 prevents the release of arachidonic acid, precursor for inflammatory mediator prostaglandins and leukotrienes, from the cell membrane. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leads to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production. ( NCI )] (UMLS (NCI) C0063079) =Steroid; Pharmacologic Substance ;
=(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
=HYDROCORTISONE VALERATE 0.2 % |
- 642. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole Mononitrate
- [The nitrate salt form of miconazole, an antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. (NCI04) ( NCI )] (UMLS (NCI) C0086620) =Organic Chemical; Pharmacologic Substance ;
=1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole;
[DE102] ANTIFUNGAL, TOPICAL;
[GU300] ANTI-INFECTIVES, VAGINAL;
=Miconazole 200 MG Vaginal Suppository;
MICONAZOLE NITRATE MISC. POWDER (GM);
MICONAZOLE NITRATE 3 X 200 MG;
MICONAZOLE NITRATE 200 MG;
MICONAZOLE NITRATE 100 MG;
MICONAZOLE NITRATE 2 % | - 692. 11D10
- [A murine monoclonal anti-idiotype antibody (anti-Id). Anti-Id 11D10 mimics a specific epitope of the high molecular weight human milk fat globule (HMFG) glycoprotein primarily expressed by human breast and some other tumor cells at high density. This specific HMFG epitope is identified by mAb BrE1, which was used as the immunizing antibody or Ab1 to generate the anti-Id (Ab2) 11D10. Anti-ID 11D10 reacts specifically with breast tumor cells and with minimal reactivity with normal tissues. Vaccination with anti-Id 11D10 induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope. ( NCI )] (UMLS (NCI) C0677765) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 643. 1-[2-[4-(3,4-Dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]ethyl]pyrrolidine Hydrochloride
- [The hydrochloride salt of the partial estrogen antagonist nafoxidine. Nafoxidine competes with endogenous estrogen for binding to specific estrogen receptors. This agent also inhibits angiogenesis in some tissues by blocking the effects of fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF); paradoxically, it may enhance angiogenesis in uterine tissue. Nafoxidine also induces oxidative stress, protein kinase C and calcium signaling. (NCI04) ( NCI )] (UMLS (NCI) C0205850) =Organic Chemical; Pharmacologic Substance
| - 693. 11D10 Anti-Idiotype Vaccine
- [A vaccine consisting of a monoclonal antibody (MoAB) directed against an idiotype that mimics a human milk fat globule (HMFG) membrane epitope. Vaccination with monoclonal antibody 11D10 anti-idiotype vaccine induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope. (NCI04) ( NCI )] (UMLS (NCI) C0935720) Monoclonal Antibody 11D10 Anti-Idiotype Vaccine;
TriAb anti-idiotype antibody =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor |
- 644. 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]pyrrolidine
- [A drug that blocks the effects of estrogen. ( NCI )] (UMLS (NCI) C0139560) =Organic Chemical; Pharmacologic Substance
| - 694. 11i
- [Maxillary left canine implant ( HL7V3.0 )] (UMLS (HL7) C1552175) =Medical Device =Artificial dentition;
|
- 645. 1-[2-{(4-chloro-phenyl)methoxy}-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Mononitrate
- [An imidazole derivative and broad-spectrum antimycotic agent with fungistatic properties. Econazole nitrate inhibits biosynthesis of ergosterol, thereby damaging the fungal cell wall membrane and altering its permeability which leads to a loss of essential intracellular components. In addition, econazole nitrate inhibits biosynthesis of triglycerides and phospholipids and inhibits oxidative and peroxidative enzyme activity which may contribute to cellular necrosis and cell death. Econazole nitrate is also active against some gram positive bacteria. This antifungal agent is used in the treatment various dermatomycoses. ( NCI )] (UMLS (NCI) C0546862) =Organic Chemical; Pharmacologic Substance =ECONAZOLE;
=ECONAZOLE NITRATE 1 %;
| - 695. 11p
- [Maxillary left canine prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553568) =Body Part, Organ, or Organ Component =Artificial dentition;
|
- 646. 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile Monohydrobromide
- [The orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), citalopram selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA). ( NCI )] (UMLS (NCI) C0724555) Citalopram Hydrobromide;
CITALOPRAM HYDROBROMIDE PREPARATION =Organic Chemical; Pharmacologic Substance ;
=citalopram;
=CITALOPRAM HYDROBROMIDE 20 MG;
CITALOPRAM HYDROBROMIDE 40 MG;
CITALOPRAM HYDROBROMIDE 10 MG/5ML | - 696. 11pd
- [Maxillary left canine distal prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553569) =Medical Device =Artificial dentition;
|
- 647. 1-[4-Chloroanilino]-4-[4-pyridylmethyl]phthalazine Succinate
- [An orally bioavailable anilinophthalazine with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms. ( NCI )] (UMLS (NCI) C0912586) 1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, butanedioate (1:1);
Butanedioic Acid, Compd. with N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (1:1);
PTK 787/ZK 222584;
VATALANIB =Organic Chemical; Pharmacologic Substance | - 697. 11pm
- [Maxillary left canine mesial prosthesis ( HL7V3.0 )] (UMLS (HL7) C1553567) =Medical Device =Artificial dentition;
|
- 648. 1-[5-guanidino-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methyl-piperidine-2-carboxylic acid
- [A synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This agent reversibly binds to the thrombin active site thereby preventing the thrombin-dependent reactions, which include conversion of fibrinogen to fibrin; the activation of factors V, VIII and XI; the activation of protein C; and platelet aggregation. Argatroban is highly selective for thrombin and is able to inhibit the action of both free and clot-associated thrombin. As a result, stabilization of blood clots and coagulation is inhibited. ( NCI )] (UMLS (NCI) C0048470) =Organic Chemical; Pharmacologic Substance =[BL100] ANTICOAGULANTS;
Pipecolic Acids =ARGATROBAN 100 MG/ML | - 698. 11q
- [Distal (long) arm of chromosome 11 ( NCI )] (UMLS (NCI) C0796366) Chromosome 11 Distal Arm;
Chromosome 11 Long Arm;
Chromosome 11q =Nucleotide Sequence |
- 649. 1-[[5-[[2-(Carboxymethyl)-3-[[decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]methoxy]-4-methoxy-1,4-dioxobutoxy]methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]methoxy]-1,2,3-propanetricarboxylic Acid, 1,2-Dimethyl Ester
- (UMLS (NCI) C0111136) =Organic Chemical
| - 699. 11q23
- [A chromosome band present on 11q ( NCI )] (UMLS (NCI) C0796367) Chromosome 11q23 =Nucleotide Sequence
|
- 650. 1.6605402 x 10-24 g
- [The non-SI unit of mass in terms of which the masses of individual atoms and molecules are expressed. Unified atomic mass unit is defined as one one twelfth of the mass of an unbound atom of the carbon-12 nuclide, the predominant isotope of carbon, at rest and in its ground state. It is equal to 1.6606x10(E-27) kg (approximately). ( NCI )] (UMLS (NCI) C0678223) =Quantitative Concept ;
| - 700. 11s
- [Supernumerary maxillary left canine ( HL7V3.0 )] (UMLS (HL7) C1552125) =Body Part, Organ, or Organ Component =SUPERNUMERARY TEETH;
|
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